Risk factors for posterior vitreous detachment: A case-control study

Risk factors for posterior vitreous detachment: A case-control study
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DOI:
10.1016/j.ajo.2006.08.002
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发表时间:
2006-12-01
影响因子:
4.2
通讯作者:
Maberley, David A. L.
Maberley, David A. L.
中科院分区:
医学1区
文献类型:
--
作者:
Chuo, Jean Y.;Lee, Tracy Y. Y.;Maberley, David A. L.

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目的:探讨玻璃体后脱离(PVD)发生的可能危险因素。设计:回顾性病例对照研究。方法:从两个不同的地点收集了138例PVD患者和114例年龄匹配的对照组。通过图表回顾、问卷调查和临床检查获得人口统计学、医学、眼科和生活方式数据。一份108项的半定量食物频率问卷也被用来估计宏量和微量营养素的摄入量。采用单变量和多变量回归分析来确定与PVD主要结局指标显著相关的变量。对性别变量进行亚组分析。结果:在所有患者中,多因素回归分析显示女性(优势比[OR] = 2.01, P = 0.016)、近视屈光(OR = 4.32, P = 0.016)
center dot PURPOSE: To identify possible risk factors for the development of posterior vitreous detachment (PVD).center dot DESIGN: Retrospective case-control study.center dot METHODS: A total of 138 cases with PVD and 114 age-matched controls were accrued from two different sites. Demographic, medical, ocular, and lifestyle data were obtained through chart review, questionnaires, and clinical examination. A 108,item semiquantitative food frequency questionnaire was also used to estimate macro- and micronutrient intake. Univariate and multivariate regression analyses were employed to identify variables significantly associated with the main outcome measure of PVD. Subgroup analysis of gender-specific variables was performed.center dot RESULTS: Among all patients, multivariate regression analysis demonstrated female gender (odds ratio [OR] = 2.01, P =.016), myopic refraction (OR = 4.32, P