Selecting a Laboratory Information Management System for Biorepositories in Low- and Middle-Income Countries: The H3Africa Experience and Lessons Learned

Selecting a Laboratory Information Management System for Biorepositories in Low- and Middle-Income Countries: The H3Africa Experience and Lessons Learned
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DOI:
10.1089/bio.2017.0006
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发表时间:
2017-04-01
影响因子:
1.6
通讯作者:
Swartz, Garth
Swartz, Garth
中科院分区:
生物学4区
文献类型:
--
作者:
Kyobe, Samuel;Musinguzi, Henry;Swartz, Garth

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非洲的生物信息库需要大量的基础设施支持,以满足国际生物与环境信息库协会(ISBER)的最佳做法,以支持基于人口的基因组研究。Isber推荐了一个生物库信息管理系统,它可以管理从生物检疫收据到分发的工作流程。H3非洲倡议开始开发非洲地区的生物库,乌干达、尼日利亚和南非成功地获得了开发最先进的生物库的赠款。生物储存库开展了一项详细的程序,以评估和选择实验室信息管理系统,目的是整合这三个地理上不同的地点。在这篇文章中,我们回顾了非洲的进程、非洲的经验和吸取的教训,并就在非洲背景下选择LIMS提出了建议。
Biorepositories in Africa need significant infrastructural support to meet International Society for Biological and Environmental Repositories (ISBER) Best Practices to support population-based genomics research. ISBER recommends a biorepository information management system which can manage workflows from biospecimen receipt to distribution. The H3Africa Initiative set out to develop regional African biorepositories where Uganda, Nigeria, and South Africa were successfully awarded grants to develop the state-of-the-art biorepositories. The biorepositories carried out an elaborate process to evaluate and choose a laboratory information management system (LIMS) with the aim of integrating the three geographically distinct sites. In this article, we review the processes, African experience, lessons learned, and make recommendations for choosing a biorepository LIMS in the African context.