Vagal and sympathetic activity during spinal analgesia
Vagal and sympathetic activity during spinal analgesia
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脊髓镇痛期间的迷走神经和交感神经活动
DOI：
10.1111/j.1399-6576.1990.tb03084.x
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发表时间：
1990
影响因子：
2.1
通讯作者：
J. Löfström
中科院分区：
文献类型：
--
作者：
P. Cook;L. Malmqvist;M. Bengtsson;B. Tryggvason;J. Löfström
本文对30例老年男性进行了迷走神经和交感神经活动指标的研究，以阐明它们在脊髓镇痛时引起低血压的可能作用。脊髓镇痛技术和静脉输液方案被标准化。迷走神经活动指数来自ECG记录上的心率变化程度（连续RR间期变化）。交感神经活性的变化进行了评估，在15例患者的皮肤电导（SCR）。针刺镇痛达到T5-6（范围T2-T10）的中位数皮节水平的15分钟。低血压与镇痛水平相关，更有可能当脊髓镇痛高于T5。迷走神经活动与低血压程度无相关性。皮肤电反应的抑制与低血压的程度和迷走神经活动无关。迷走神经传出活动，在心脏测量，似乎并没有发挥一个原因的作用，在脊髓镇痛期间发生的低血压。
Indices of vagal and sympathetic activity were studied in 30 elderly males, to elucidate their possible roles in causing hypotension during spinal analgesia. The technique of spinal analgesia and the regimen of intravenous fluids were standardised. An index of vagal activity was derived from the degree of heart rate variation (successive RR interval change) on ECG recordings. Sympathetic activity was evaluated by changes in the skin conductance (SCR) of 15 patients. Analgesia to pinprick reached a median dermatome level of T5–6 (range T2–T10) by 15 min. Hypotension was correlated with the level of analgesia, and was more likely when spinal analgesia was higher than T5. There was no correlation between vagal activity and the degree of hypotension. The depression of skin conductance responses was not correlated with the degree of hypotension nor with vagal activity. Vagal efferent activity, measured at the heart, does not seem to play a causative role in hypotension occurring during spinal analgesia.