C. elegans behavior of preference choice on bacterial food
C. elegans behavior of preference choice on bacterial food
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DOI：
10.1007/s10059-009-0124-x
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发表时间：
2009-09-01
影响因子：
3.8
通讯作者：
Ahnn, Joohong
中科院分区：
文献类型：
--
作者：
Abada, Emad Abd-elmoniem;Sung, Hyun;Ahnn, Joohong
秀丽线虫是一种自由生活的土壤线虫，因此在其自然栖息地，秀丽线虫会遇到许多不同种类的土壤细菌。虽然一些土壤细菌可能是蠕虫的极好营养来源，但其他细菌可能是致病的。因此，我们开展了一项研究，以了解线虫如何使用简单的行为测试来识别它们喜欢的食物。我们发现，与标准实验室菌株OP50相比，线虫喜欢的土壤细菌种类繁多。特别是，两个细菌菌株，芽孢杆菌和芽孢杆菌，是首选的菌株。有趣的是，只给野生动物喂食这些细菌会通过激活自噬过程而延长寿命。需要进一步的研究来了解控制线虫识别和选择食物行为的精确机制。
Caenorhabditis elegans is a free living soil nematode and thus in its natural habitat, C. elegans encounters many different species of soil bacteria. Although some soil bacteria may be excellent sources of nutrition for the worm, others may be pathogenic. Thus, we undertook a study to understand how C. elegans can identify their preferred food using a simple behavioral assay. We found that there are various species of soil bacteria that C. elegans prefers in comparison to the standard laboratory E. coli strain OP50. In particular, two bacterial strains, Bacillus mycoides and Bacillus soli, were preferred strains. Interestingly, the sole feeding of these bacteria to wild type animals results in extended lifespan through the activation of the autophagic process. Further studies will be required to understand the precise mechanism controlling the behavior of identification and selection of food in C. elegans.