Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
Isolation and characterization of Korean porcine deltacoronavirus strain KNU16-07
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DOI：
10.4142/jvs.2018.19.4.586
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发表时间：
2018-07-01
影响因子：
1.8
通讯作者：
Lee, Changhee
中科院分区：
文献类型：
--
作者：
Jang, Guehwan;Kim, Seong-Hee;Lee, Changhee
Porcine deltacoronavirus (PDCoV) has emerged in several pig-raising countries and has been a causative pathogen associated with diarrheal diseases in South Korea since 2014. In the present study, we were able to isolate and cultivate a Korean PDCoV strain (KNU16-07) in cell culture and investigate its pathogenicity. PDCoV-inoculated piglets showed watery diarrhea accompanied by acute enteritis in the natural host. Sequencing analysis demonstrated the genetic stability of KNU16-07 for at least thirty serial passages.
