A novel diol-derivative of chalcone produced by bioconversion, 3-(2, 3-dihydroxyphenyl)-1-phenylpropan-1-one, activates PKA/MEK/ERK signaling and antagonizes A.-inhibition of the cascade in cultured rat CNS neurons.
A novel diol-derivative of chalcone produced by bioconversion, 3-(2, 3-dihydroxyphenyl)-1-phenylpropan-1-one, activates PKA/MEK/ERK signaling and antagonizes A.-inhibition of the cascade in cultured rat CNS neurons.
复制标题
通过生物转化产生的一种新型查耳酮二醇衍生物 3-(2, 3-二羟基苯基)-1-苯基丙-1-酮,可激活 PKA/MEK/ERK 信号传导并拮抗培养的大鼠 CNS 神经元中级联的 A.-抑制
DOI:
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发表时间:
2008
期刊:
影响因子:
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通讯作者:
Ohizumi Y & Yamakuni T.
中科院分区:
文献类型:
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作者:
Md. Al Rahim;Nakajima A;Misawa N;Shindo K;Adachi K;Shizuri Y;Ohizumi Y & Yamakuni T.