[2-C-14]DEOXYGLUCOSE UPTAKE IN RAT VISUAL-SYSTEM DURING FLASHING-DIFFUSE AND FLASHING-PATTERN STIMULATION OVER A 6 LOG RANGE OF LUMINANCE
[2-C-14]DEOXYGLUCOSE UPTAKE IN RAT VISUAL-SYSTEM DURING FLASHING-DIFFUSE AND FLASHING-PATTERN STIMULATION OVER A 6 LOG RANGE OF LUMINANCE
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DOI：
10.1016/0014-4886(91)90149-7
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发表时间：
1991-07-01
影响因子：
5.3
通讯作者：
THURLOW, GA
中科院分区：
文献类型：
--
作者：
COOPER, RM;THURLOW, GA
2-脱氧葡萄糖放射自显影技术用于评估皮质区域 17、背侧和腹侧外侧膝状体核、外侧后核和上丘在 6 对数范围内的三种强度的 5 Hz 闪烁模式（黑白方波光栅的蒙太奇）和闪烁漫射（用白色面罩覆盖的眼睛）刺激期间的代谢活动。在区域 17 中，闪烁模式被发现在提高功能标签在测试的明视-暗视范围的亮度水平方面同样有效，而闪烁漫射则无效。然而，在皮质下核中，闪烁漫射的效果并不亚于闪烁模式，并且标签的摄取与强度水平呈正相关。结果表明，视觉系统的皮层下成分确实在强度信息的处理中发挥着重要作用，而初级视觉皮层则不然。
The 2-deoxyglucose autoradiographic technique was used to assess the metabolic activity of cortical area 17, the dorsal and ventral lateral geniculate nuclei, the lateral posterior nucleus, and the superior colliculus, during 5-Hz flashing-pattern (montage of black and white square-wave gratings) and flashing-diffuse (eye covered with white mask) stimulation at three intensities over a 6 log range. In area 17 flashing-pattern was found to be equally effective at elevating uptake of the functional label over the photopic-scotopic range of luminance levels tested, whereas flashing-diffuse was ineffective. In subcortical nuclei, however, flashing-diffuse was no less effective than flashing-pattern and uptake of the label correlated positively with intensity level. The results suggest that the subcortical components of the visual system do play an important role in the processing of intensity information and that primary visual cortex does not.