Mechanism and circuitry for clustering and fine discrimination of odors in insects.
Mechanism and circuitry for clustering and fine discrimination of odors in insects.
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昆虫气味聚类和精细辨别的机制和电路。
DOI：
10.1073/pnas.0407858101
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发表时间：
2004
影响因子：
11.1
通讯作者：
Kopell,Nancy
中科院分区：
文献类型：
--
作者：
Sivan,Ehud;Kopell,Nancy
气味识别包括聚类和精细辨别。聚类将多组气味连接在一起，并且精细辨别可以区分属于同一簇的气味。我们假设气味识别的这两个方面是由昆虫嗅觉系统的两个大脑区域并行编码的。侧角神经元的群体活动编码气味簇，蘑菇体神经元的群体活动编码气味的精细特征。我们的机制基于这样的假设：昆虫嗅觉系统的底层网络由重复的、硬连线的子结构组成，我们描述了其解剖结构。我们表明，这些提出的机制和电路不仅解释了系统中观察到的神经元数量和连接，还解释了观察到的这些神经元的活动，以及为什么振荡对于精细辨别至关重要，但对于气味聚类却不是。
Odor recognition encompasses both clustering and fine discrimination. Clustering joins together sets of odors, and fine discrimination distinguishes between odors belonging to the same cluster. We hypothesize that these two aspects of odor recognition are encoded in parallel by two brain areas of the insect olfactory system. Population activity of neurons in the lateral horn encodes the odor cluster, and population activity of neurons in the mushroom body encodes the fine identity of the odor. Our mechanism is based on the hypothesis that the underlying network of the insect olfactory system consists of a repetitive, hard-wired substructure whose anatomy we describe. We show that these suggested mechanisms and circuitry explain not only the observed numbers and connections of neurons in the system, but also the observed activity of these neurons, and why oscillations are critical for fine discrimination but not for clustering of odors.