Outcomes for out-of-hospital cardiac arrests across 7 countries in Asia: The Pan Asian Resuscitation Outcomes Study (PAROS)

Outcomes for out-of-hospital cardiac arrests across 7 countries in Asia: The Pan Asian Resuscitation Outcomes Study (PAROS)
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DOI:
10.1016/j.resuscitation.2015.07.026
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发表时间:
2015-11-01
期刊:
影响因子:
6.5
通讯作者:
Ma, Matthew Huei-Ming
Ma, Matthew Huei-Ming
中科院分区:
医学2区
文献类型:
--
作者:
Ong, Marcus Eng Hock;Shin, Sang Do;Ma, Matthew Huei-Ming

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背景:泛亚复苏结果研究(PAROS)临床研究网络(CRN)是由日本、新加坡、韩国、马来西亚、台湾、泰国和阿联酋迪拜的紧急医疗服务(EMS)机构和学术中心合作建立的,旨在报告院外心脏骤停(OHCA),并更好地了解亚洲的OHCA趋势。方法和结果:这是一项亚太地区OHCA的前瞻性、国际性、多中心队列研究。每个参与国提供了2009年1月至2012年12月期间1.5至2.5年的数据。所有由EMS转诊或在急诊科就诊的OHCA病例均被收集OHCA病例提交给PAROS CRN;推断为心脏病因41004例。OHCA发生的平均年龄为49.7 ~ 71.7岁。男性占比57.9% ~ 82.7%。无证人逮捕的比例从26.4%到67.9%不等。表现为休克节律率在4.1% ~ 19.8%之间。旁观者心肺复苏(CPR)率从10.5%到40.9%不等,但这些骤停患者中只有不到1.0%接受了旁观者除颤。对于心脏病因、目睹骤停和室性心动过速的骤停,到出院的存活率从无幸存者到31.2%不等。到出院的总生存率从0.5%到8.5%不等。神经功能良好的生存率为1.6% - 3%。结论:亚洲患者的出院生存率差异很大,这可能与患者和系统的差异有关。这意味着生存率可以通过增加旁观者心肺复苏术、公共场所除颤和改善EMS等干预措施来提高。2015爱思唯尔爱尔兰有限公司版权所有。
Background: The Pan Asian Resuscitation Outcomes Study (PAROS) Clinical Research Network (CRN) was established in collaboration with emergency medical services (EMS) agencies and academic centers in Japan, Singapore, South Korea, Malaysia, Taiwan, Thailand, and UAE-Dubai and aims to report out-of-hospital cardiac arrests (OHCA) and provide a better understanding of OHCA trends in Asia.Methods and results: This is a prospective, international, multi-center cohort study of OHCA across the Asia-Pacific. Each participating country provided between 1.5 and 2.5 years of data from January 2009 to December 2012. All OHCA cases conveyed by EMS or presenting at emergency departments were captured.66,780 OHCA cases were submitted to the PAROS CRN; 41,004 cases were presumed cardiac etiology. The mean age OHCA occurred varied from 49.7 to 71.7 years. The proportion of males ranged from 57.9% to 82.7%. Proportion of unwitnessed arrests ranged from 26.4% to 67.9%. Presenting shockable rhythm rates ranged from 4.1% to 19.8%. Bystander cardiopulmonary resuscitation (CPR) rates varied from 10.5% to 40.9%, however < 1.0% of these arrests received bystander defibrillation. For arrests that were with cardiac etiology, witnessed arrest and VF, the survival rate to hospital discharge varied from no reported survivors to 31.2%. Overall survival to hospital discharge varied from 0.5% to 8.5%. Survival with good neurological function ranged from 1.6% to 3%.Conclusions: Survival to hospital discharge for Asia varies widely and this may be related to patient and system differences. This implies that survival may be improved with interventions such as increasing bystander CPR, public access defibrillation and improving EMS. (C) 2015 Elsevier Ireland Ltd. All rights reserved.