Supersonic shear imaging: A new technique for soft tissue elasticity mapping
Supersonic shear imaging: A new technique for soft tissue elasticity mapping
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DOI：
10.1109/tuffc.2004.1295425
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发表时间：
2004-04-01
影响因子：
3.6
通讯作者：
Fink, M
中科院分区：
文献类型：
--
作者：
Bercoff, J;Tanter, M;Fink, M
超声剪切成像(SSI)是一种基于超声的实时显示软组织粘弹性特性的新技术。使用超声聚焦波束，可以远程产生辐射组织内低频剪切波的机械振动源。基于这一概念，SSI建议创造这样一个震源，并使其以超音速移动。类似于超音速飞机产生的“音爆”，产生的剪切波将沿马赫锥体建设性地干涉，产生两个强烈的平面剪切波。这些波通过介质传播，并因组织的非均质性而逐渐失真。一台超快扫描仪样机既能产生这种超音速声源，又能成像(5000帧/S)所产生的横波的传播。利用反演算法，可以从这一传播电影中定量地绘制出介质的剪切弹性图。SSI能够在不到20英寸的时间内绘制组织弹性图，即使在像乳房这样的粘性很强的介质中也是如此。通过在不同方向倾斜横波和改进弹性估计，可以实现剪切复合等模式。结果验证了异质模体中SSI的有效性。首次在健康志愿者身上进行的体内研究强调了SSI在乳腺癌检测中的潜在临床适用性。
Supersonic shear imaging (SSI) is a new ultrasound-based technique for real-time visualization of soft tissue viscoelastic properties. Using ultrasonic focused beams, it is possible to remotely generate mechanical vibration sources radiating low-frequency, shear waves inside tissues. Relying on this concept, SSI proposes to create such a source and make it move at a supersonic speed. In analogy with the "sonic boom" created by a supersonic aircraft, the resulting shear waves will interfere constructively along a Mach cone, creating two intense plane shear waves. These waves propagate through the medium and are progressively distorted by tissue heterogeneities. An ultrafast scanner prototype is able to both generate this supersonic source and image (5000 frames/s) the propagation of the resulting shear waves. Using inversion algorithms, the shear elasticity of medium can be mapped quantitatively from this propagation movie. The SSI enables tissue elasticity mapping in less than 20 ins, even in strongly viscous medium like breast. Modalities such as shear compounding are im-plementable by tilting shear waves in different directions and improving the elasticity estimation. Results validating SSI in heterogeneous phantoms are presented. The first in vivo investigations made on healthy volunteers emphasize the potential clinical applicability of SSI for breast cancer detection.