Prevalence of familial occurrence in patients with rheumatoid arthritis.

Prevalence of familial occurrence in patients with rheumatoid arthritis.
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类风湿性关节炎患者的家族发病率。

DOI:
10.1093/rheumatology/xxvii.suppl_2.150
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发表时间:
1988
期刊:
British journal of rheumatology
影响因子:
--
通讯作者:
Khan,MA
Khan,MA
中科院分区:
--
文献类型:
--
作者:
Wolfe,F;Kleinheksel,SM;Khan,MA

文献摘要

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我们对 1976 年 4 月至 1986 年 8 月间关节炎诊所的 985 名确诊或典型类风湿性关节炎 (RA) 患者进行了连续研究,以调查家族性疾病的患病率。我们已经证明,至少 10.9% 的患有明确或经典 RA 的无关患者有一个或多个一级亲属患有明确或经典 RA。此外,家族性 RA 并不比更常见的非家族性(即散发性)疾病形式更严重。
We studied 985 consecutive patients with definite or classical rheumatoid arthritis (RA) at an arthritis clinic, between April 1976 and August 1986, to investigate the prevalence of familial disease. We have demonstrated that at least 10.9% of unrelated patients with definite or classical RA have one or more first-degree relative(s) affected with definite or classical RA Moreover, familial RA is not more severe than the more prevalent non-familial, i.e. sporadic, form of the disease.