A FOLLOW-UP-STUDY ON SPASTIC PARAPARESIS IN JAPANESE HAM/TSP

A FOLLOW-UP-STUDY ON SPASTIC PARAPARESIS IN JAPANESE HAM/TSP
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DOI:
10.1016/0022-510x(95)00142-o
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发表时间:
1995-10-01
影响因子:
4.4
通讯作者:
MATSUI, M
MATSUI, M
中科院分区:
医学3区
文献类型:
--
作者:
KURODA, Y;YUKITAKE, M;MATSUI, M

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我们对24例HTLV-I相关性脊髓病(HAM)患者进行了4-12年(平均7年)的随访,并采用Kurtzke残疾状态量表(DSS)评估了痉挛性下肢轻瘫的纵向变化。在随访期间,18例患者(75%)痉挛性轻瘫的DSS评分无变化,1例患者中有2例和3例患者中有1例进展(恶化),2例患者中有1例下降(改善)。结果表明,HAM呈现出多种临床过程,包括自发改善。
We followed 24 patients with HTLV-I-associated myelopathy (HAM) for 4-12 years (mean 7 years) and assessed longitudinal changes of their spastic paraparesis by Kurtzke's Disability Status Scale (DSS). The DSS score of spastic paraparesis was unchanged in 18 patients (75%), advanced (worsened) by two in 1 patient and by one in 3 patients, and declined (improved) by one in 2 patients during the follow-up period. The results demonstrated that HAM presents with a variety of clinical courses including spontaneous improvement.