The impact of diabetes-related complications on healthcare costs: new results from the UKPDS (UKPDS 84)
The impact of diabetes-related complications on healthcare costs: new results from the UKPDS (UKPDS 84)
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DOI：
10.1111/dme.12647
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发表时间：
2015-04-01
影响因子：
3.5
通讯作者：
Holman, R. R.
中科院分区：
文献类型：
--
作者：
Alva, M. L.;Gray, A.;Holman, R. R.
目的估计2型糖尿病相关并发症的即时和长期住院和非住院费用。1997年至1999年期间英国前瞻性糖尿病研究试验后监测期间与糖尿病相关并发症相关的入院和手术2007年估计使用住院记录的2791例患者在英国和资源使用问卷，管理到3589例患者在英国各地。估计（95% CI）住院治疗费用（以2012年英镑为单位）在事件年份中以60岁男性为例分别为：非致命性缺血性心脏病9767（7038磅12磅696）;截肢9546磅（6416磅13磅463）;非致命性中风6805磅（3856磅10磅278）;非致命性心肌梗死6379磅（4290- 8339磅）;致命中风3954磅（2012年-6428磅）;致命的缺血性心脏病3766磅（746磅5512）;心力衰竭3191磅（1678-4903）;磅致命的心肌梗塞1521磅（647- 2670磅）;磅和一只眼睛失明1355磅（415- 2655磅）。在随后的几年中，估计（95% CI）的成本范围从1792磅（1060磅2943）英镑截肢到453磅（315磅691）英镑的单眼失明。事件年份非住院医疗费用为：截肢2699磅（1409- 4126磅）;一只眼睛失明1790磅（878磅3056）;磅非致命中风1019磅（770磅1499）;磅非致命性心肌梗死1963磅（794-磅1157）;心力衰竭磅979磅（708磅1344）;磅非致命性缺血性心脏病864磅（718磅1014）;磅和白内障摘除700磅（619磅780）磅。在随后的每一年中，非住院费用范围从1611磅（1193磅2116）磅截肢654磅（572磅799）磅缺血性心脏病。我们对这些费用的全面新估计，来自最近英国前瞻性糖尿病研究试验后的详细数据，应该有助于研究人员和卫生政策分析。
AimsTo estimate the immediate and long-term inpatient and non-inpatient costs for Type 2 diabetes-related complications.MethodsThe costs of all consultations, visits, admissions and procedures associated with diabetes-related complications during UK Prospective Diabetes Study post-trial monitoring in the period 1997-2007 were estimated using hospitalization records for 2791 patients in England and resource use questionnaires that were administered to 3589 patients across the UK.ResultsThe estimated (95% CI) inpatient care costs (in 2012 pounds sterling) in the event year for the example of a 60-year-old man were: non-fatal ischaemic heart disease 9767 (7038- pound 12 pound 696); amputation 9546 pound (6416- pound 13 pound 463); non-fatal stroke 6805 pound (3856- pound 10 pound 278); non-fatal myocardial infarction 6379 pound (4290- pound 8339); pound fatal stroke 3954 pound (2012- pound 6428); pound fatal ischaemic heart disease 3766 pound (746- pound 5512); pound heart failure 3191 pound (1678-4903); pound fatal myocardial infarction 1521 pound (647- pound 2670); pound and blindness in one eye 1355 pound (415- pound 2655) pound. In subsequent years, estimated (95% CI) costs ranged from 1792 pound (1060- pound 2943) pound for amputations to 453 pound (315- pound 691) pound for blindness in one eye. Costs of non-inpatient healthcare in the event year were: amputation 2699 pound (1409- pound 4126); pound blindness in one eye 1790 pound (878- pound 3056); pound non-fatal stroke 1019 pound (770- pound 1499); pound nonfatal myocardial infarction 1963 pound (794- pound 1157); pound heart failure 979 pound (708- pound 1344); pound non-fatal ischaemic heart disease 864 pound (718- pound 1014); pound and cataract extraction 700 pound (619- pound 780) pound. In each subsequent year, non-inpatient costs ranged from 1611 pound (1193- pound 2116) pound for amputations to 654 pound (572- pound 799) pound for ischaemic heart disease.ConclusionsDiabetic complications are associated with substantial immediate and long-term healthcare costs. Our comprehensive new estimates of these costs, derived from detailed recent UK Prospective Diabetes Study post-trial data, should aid researchers and health policy analyses.