Maternal-fetal transfer and metabolism of vitamin A and its precursor β-carotene in the developing tissues.

Maternal-fetal transfer and metabolism of vitamin A and its precursor β-carotene in the developing tissues.
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维生素 A 及其前体 β-胡萝卜素在发育组织中的母胎转移和代谢。

DOI:
10.1016/j.bbalip.2011.05.003
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发表时间:
2012
期刊:
Biochimica et biophysica acta
影响因子:
--
通讯作者:
Quadro,Loredana
Quadro,Loredana
中科院分区:
--
文献类型:
--
作者:
Spiegler,Elizabeth;Kim,Youn-Kyung;Wassef,Lesley;Shete,Varsha;Quadro,Loredana

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The requirement of the developing mammalian embryo for retinoic acid is well established. Retinoic acid, the active form of vitamin A, can be generated from retinol and retinyl ester obtained from food of animal origin, and from carotenoids, mainly β-carotene, from vegetables and fruits. The mammalian embryo relies on retinol, retinyl ester and β-carotene circulating in the maternal bloodstream for its supply of vitamin A. The maternal–fetal transfer of retinoids and carotenoids, as well as the metabolism of these compounds in the developing tissues are still poorly understood. The existing knowledge in this field has been summarized in this review in reference to our basic understanding of the transport and metabolism of retinoids and carotenoids in adult tissues. The need for future research on the metabolism of these essential lipophilic nutrients during development is highlighted. This article is part of a Special Issue entitled: Retinoid and Lipid Metabolism.
视黄酸可由人肠粘膜中β-胡萝卜素的偏心裂解产生。
DOI: 10.1016/0003-9861(92)90399-h
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DOI: --
发表时间: 1964
期刊: Proceedings of the Royal Society of London. Series B. Biological Sciences
影响因子: --
作者:
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