Simultaneous bilateral central retinal vein occlusion associated with anticardiolipin antibodies in leukemia.

Simultaneous bilateral central retinal vein occlusion associated with anticardiolipin antibodies in leukemia.
复制标题

白血病中与抗心磷脂抗体相关的同时双侧视网膜中央静脉阻塞。

DOI:
10.1016/s0002-9394(01)00911-4
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发表时间:
2001
影响因子:
4.2
通讯作者:
LaBorwit,SE
LaBorwit,SE
中科院分区:
医学1区
文献类型:
--
作者:
Al-Abdulla,NA;Thompson,JT;LaBorwit,SE

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目的报告一例伴有白血病和抗心磷脂自身抗体的双侧视网膜中央静脉阻塞。方法采用常规病例报告。我们对一位65岁男性慢性髓性白血病患者进行了临床检查、荧光素血管造影、b超和实验室血清学检查,他表现为右眼突发性视力下降。结果眼底检查发现非缺血性视网膜中央静脉阻塞。在接下来的3周内,双眼出现非灌注性视网膜中央静脉阻塞,随后左眼出现新生血管性青光眼。在此期间,他的白细胞和血小板计数保持正常,他的血清粘度保持低,但抗心磷脂抗体增加。结论本病例揭示了白血病患者并发双侧视网膜中央静脉闭塞与抗心磷脂抗体相关,提示白血病患者双侧视网膜中央静脉闭塞除高粘稠度外还有其他机制。
PURPOSETo present a dramatic case of simultaneous bilateral central retinal vein occlusion associated with leukemia and anticardiolipin autoantibodies.METHODSInterventional case report. Clinical examination, fluorescein angiography, B-mode ultrasonography, and laboratory serologies were performed on a 65-year-old man with chronic myelogenous leukemia who presented with sudden onset of decreased vision in his right eye.RESULTSFundus examination disclosed a nonischemic central retinal vein occlusion. Over the next 3 weeks, a nonperfused central retinal vein occlusion developed in both eyes and subsequent neovascular glaucoma developed in his left eye. Throughout this time, his white blood cell and platelet counts remained normal and his serum viscosity remained low, but anticardiolipin antibodies were increased.CONCLUSIONThis case reveals the occurrence of simultaneous bilateral central retinal vein occlusion associated with anticardiolipin antibodies in leukemia and suggests an additional mechanism other than hyperviscosity for bilateral central retinal vein occlusions in leukemic patients.
无危险因素患者的抗磷脂抗体与视网膜血栓形成
DOI: --
发表时间: 2000
期刊:
影响因子: --
作者:
Rosario Cobo;Silvia Sánchez;M. Aparicio
通讯作者: M. Aparicio