The role of Area 17 in visual imagery: Convergent evidence from PET and rTMS
The role of Area 17 in visual imagery: Convergent evidence from PET and rTMS
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DOI：
10.1126/science.284.5411.167
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发表时间：
1999-04-02
期刊：
影响因子：
56.9
通讯作者：
Alpert, NM
中科院分区：
文献类型：
--
作者：
Kosslyn, SM;Pascual-Leone, A;Alpert, NM
视觉表象被用于从记忆到推理等广泛的心理活动中，并且在正常的感知中也起作用。通过使用两种聚合技术，研究了早期视觉皮层，特别是17区，对视觉心理表象的贡献。在一种技术中，被试在正电子发射断层扫描（PET）期间闭上眼睛，同时想象并比较几组条纹的属性（例如，相对长度）。结果表明，当人们执行这项任务时，17区被激活。在另一种技术中，在呈现相同任务之前，对枕叶内侧皮层施加重复性经颅磁刺激（rTMS）。与假对照条件相比，经rTMS刺激后被试的表现受损；当被试实际观察刺激来执行任务时，也得到了类似的结果。总之，PET结果表明，当条纹图案被想象时，17区被激活，并且rTMS结果表明这种激活是信息处理的基础。
Visual imagery is used in a wide range of mental activities, ranging from memory to reasoning, and also plays a role in perception proper. The contribution of early visual cortex, specifically Area 17, to Visual mental imagery was examined by the use of two convergent techniques. In one, subjects closed their eyes during positron emission tomography (PET) while they visualized and compared properties (for example, relative length) of sets of stripes. The results showed that when people perform this task, Area 17 is activated. In the other, repetitive transcranial magnetic stimulation (rTMS) was applied to medial occipital cortex before presentation of the same task. Performance was impaired after rTMS compared with a sham control condition; similar results were obtained when the subjects performed the task by actually Looking at the stimuli. In sum, the PET results showed that when patterns of stripes are visualized, Area 17 is activated, and the rTMS results showed that such activation underlies information processing.