Role of lymph node dissection for intrahepatic cholangiocarcinoma.
Role of lymph node dissection for intrahepatic cholangiocarcinoma.
复制标题
淋巴结清扫术在肝内胆管癌中的作用。
DOI：
10.1200/jco.2017.35.4_suppl.457
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Y. Kitagawa
中科院分区：
文献类型：
--
作者：
T. Hibi;Yusuke Takemura;O. Itano;M. Shinoda;M. Kitago;Y. Abe;H. Yagi;Y. Kitagawa
背景：肝内胆管细胞癌（ICC）伴淋巴结转移的预后很差。最近的研究从疾病分期和治疗的角度强调了淋巴结切除的重要性。为了明确淋巴结清扫在ICC中的作用，本研究旨在评估ICC的淋巴结转移模式及其预后意义。方法：对1990年至2015年间因ICC接受R 0/R1切除术的56例连续患者进行了回顾性队列分析。原则上，肝门和胰头周围的淋巴结被系统地切除。对于左侧肿瘤，还解剖了胃小弯和胃左动脉根部的淋巴结。通过考克斯多变量分析确定3年生存率的临床病理学预测因素。进行淋巴结定位，并根据转移率和转移率将阳性淋巴结分为3个区室。结果：中位肿瘤大小为4.5（1...
457Background: The prognosis of intrahepatic cholangiocarcinoma (ICC) with lymph node metastases is dismal. Recent studies have highlighted the importance of lymph node retrieval from disease staging and therapeutic standpoints. To define the role of lymph node dissection for ICC, this study aimed to evaluate the patterns of lymph node metastases and their prognostic implication. Methods: A retrospective cohort analysis was conducted for 56 consecutive patients who underwent R0/R1 resection for ICC between 1990 and 2015. In principle, lymph nodes in the hepatic hilum and around the pancreas head were systematically removed. For left-sided tumors, lymph nodes in the lesser curvature of the stomach and the root of left gastric artery were also dissected. Clinicopathologic predictors of 3-year survival were identified by Cox multivariate analyses. Lymph node mapping was performed and positive nodes were classified into 3 compartments based on metastatic rates and prognoses. Results: Median tumor size, 4.5 (1...