The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity
The sensitivity and specificity of the Major Depression Inventory, using the Present State Examination as the index of diagnostic validity
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DOI：
10.1016/s0165-0327(00)00309-8
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发表时间：
2001-10-01
影响因子：
6.6
通讯作者：
Abildgaard, W
中科院分区：
文献类型：
--
作者：
Bech, P;Rasmussen, NA;Abildgaard, W
背景：已经开发了一份自我评定量表，通过患者自我报告的症状来衡量DSM-IV和ICD-10对重度(中度到重度)抑郁症的诊断。根据抑郁症状学的DSM-IV和ICD-10算法，以及根据项目的简单总和根据严重程度分级，可以对该重大抑郁量表(MDI)进行评分。方法：采用神经精神病学临床评定量表(SCAN)作为临床医生诊断重度(中、重度)抑郁症的DSM-IV和ICD-10的效度指标。MDI的敏感性和特异性在43名受试者的样本中进行了评估，涵盖了一系列抑郁症状。结果：MDI算法对抑郁症的敏感度在0.86到0.92之间。特异性在0.82~0.86之间。当使用MDI总分时，最佳分界值估计为26分，总分被证明是一个充分的统计，局限性：受试者的样本有限。患有精神病性抑郁症的患者不包括在内。结论：MDI具有较高的敏感性和特异性，是可以接受的。问卷很简单，可以通过DSM-IV和ICD-10算法以及其简单的总分进行诊断性评分。(C)2001 Elsevier Science B.V.保留所有权利。
Background: A self-rating inventory has been developed to measure DSM-IV and ICD-10 diagnoses of major (moderate to severe) depression by the patients' self-reported symptoms. This Major Depression Inventory (MDI) can be scored both according to the DSM-IV and the ICD-10 algorithms for depressive symptomatology and according to severity scales by the simple total sum of the items. Methods: The Schedule for Clinical Assessment in Neuropsychiatry (SCAN) was used as index of validity for the clinician's DSM-IV and ICD-10 diagnosis of major (moderate to severe) depression. The sensitivity and specificity of MDI was assessed in a sample of 43 subjects covering a spectrum of depressive symptoms. Results: The sensitivity of the MDI algorithms for major depression varied between 0.86 and 0.92. The specificity varied between 0.82 and 0.86. When using the total score of MDI the optimal cut-off score was estimated 26 and the total score was shown to be a sufficient statistic, Limitations: The sample of subjects was limited. Patients with psychotic depression were not included. Conclusion: The MDI was found to have a sensitivity and specificity which is acceptable. The questionnaire is brief and can be scored diagnostically by the DSM-IV and ICD-10 algorithms as well as by its simple total score. (C) 2001 Elsevier Science B.V. All rights reserved.