Human metapneumovirus: A new player among respiratory viruses
Human metapneumovirus: A new player among respiratory viruses
复制标题
DOI：
10.1086/382536
复制
发表时间：
2004-04-01
影响因子：
11.8
通讯作者：
Boivin, G
中科院分区：
文献类型：
--
作者：
Hamelin, ME;Abed, Y;Boivin, G
人偏肺病毒（hMPV）是新发现的副粘病毒科成员，属于偏肺病毒属。自2001年首次描述以来，hMPV已在世界大部分地区报告，并从所有年龄组受试者的呼吸道中分离出来。尽管前瞻性和病例对照研究有限，但hMPV的流行病学和临床表现与人类呼吸道合胞病毒有关，大多数严重的呼吸道感染发生在婴儿、老年人和免疫功能低下的宿主中。需要进一步的研究来确定这种病毒感染的发病机制和宿主的特异性免疫反应。
The human metapneumovirus (hMPV) is a newly described member of the Paramyxoviridae family belonging to the Metapneumovirus genus. Since its initial description in 2001, hMPV has been reported in most parts of the world and isolated from the respiratory tract of subjects from all age groups. Despite the fact that prospective and case-control studies have been limited, the epidemiology and clinical manifestations associated with hMPV have been found to be reminiscent of those of the human respiratory syncytial virus, with most severe respiratory tract infections occurring in infants, elderly subjects, and immunocompromised hosts. Additional research is needed to define the pathogenesis of this viral infection and the host's specific immune response.