Effect of trigeminal tractotomy on behavioral response to dental pulp stimulation in the monkey
Effect of trigeminal tractotomy on behavioral response to dental pulp stimulation in the monkey
复制标题
三叉神经束切开术对猴牙髓刺激行为反应的影响
DOI：
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发表时间：
1981
期刊：
影响因子：
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通讯作者：
K. Perryman
中科院分区：
文献类型：
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作者：
R. Young;T. Oleson;K. Perryman
在10只猕猴中进行了近闩水平的三叉神经束切断术。行为反应进行了评估，通过定量的范例测量电刺激牙髓或面部皮肤的压力反应，并通过评估面部皮肤针抓伤之前和之后的神经束切断术。给予两种药物士的宁和左旋多巴，并研究它们对这些刺激的行为反应的影响。纤维束切断术不产生牙科镇痛。然而，逃避面部皮肤的皮肤电刺激的阈值升高，与针抓的显著痛觉减退一致。在面部的周边部分不存在对针抓挠的不良反应，但在中线附近和口腔内部，它们通常减少或正常。药物引起皮肤电刺激的逃逸阈值降低，镇痛区缩小或消失。关于...
✓ Trigeminal tractotomy near the level of the obex was carried out in 10 macaque monkeys. Behavioral responses were evaluated by a quantitative paradigm measuring lever-press responses to electrical stimulation of the dental pulp or facial skin, and by assessing facial response to cutaneous pin-scratch before and after the tractotomy. Two pharmacological agents, strychnine and L-dopa, were administered and their effect on behavioral responses to these stimuli was studied. Tractotomy did not produce dental analgesia. Thresholds for escape from cutaneous electrical stimulation of facial skin, however, were elevated, consistent with marked hypalgesia to pin-scratch. The adversive responses to pin-scratch were absent in peripheral portions of the face, but near the midline and inside the oral cavity they were usually decreased or normal. Pharmacological agents caused a reduction in escape thresholds to cutaneous electrical stimulation and a shrinkage or abolition of the zone of analgesia to pinscratch. The re...