Atrazine exposure affects longevity, development time and body size in Drosophila melanogaster.
Atrazine exposure affects longevity, development time and body size in Drosophila melanogaster.
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DOI：
10.1016/j.jinsphys.2016.06.006
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发表时间：
2016-08
影响因子：
2.2
通讯作者：
Fiumera AC
中科院分区：
文献类型：
--
作者：
Marcus SR;Fiumera AC
阿特拉津是美国使用最广泛的除草剂之一，非目标生物可能会在环境中遇到它。已知阿特拉津会影响脊椎动物和无脊椎动物的雄性生殖，但对其对其他适应性特征的影响知之甚少。在这里，我们评估了五种不同的慢性暴露水平对果蝇的各种健身特征的影响。测定了雌、雄成虫的寿命、发育时间、化蛹率、羽化率、个体大小、雌虫交配率、生育力和繁殖力。阿特拉津暴露降低了化蛹率、羽化率和成虫存活率。发育时间也受到阿特拉津和暴露的苍蝇化蛹，出现早于对照组。虽然显影时间加快了，但在某些曝光中，身体尺寸实际上更大。阿特拉津暴露对雌性交配率没有影响，仅在两个独立实验区之一中观察到对雌性生育力和繁殖力的影响。许多性状表现出非单调的剂量反应曲线，其中中间浓度表现出最大的影响。总之，本研究表明，阿特拉津影响了模式遗传系统中的多种生活史性状。今后的研究应着眼于确定毒性的分子机制。
Atrazine is the one of the most widely used herbicides in the United States and non-target organisms may encounter it in the environment. Atrazine is known to affect male reproduction in both vertebrates and invertebrates but less is known about its effects on other fitness traits. Here we assessed the effects of five different chronic exposure levels on a variety of fitness traits in Drosophila melanogaster. We measured male and female longevity, development time, proportion pupated, proportion emerged, body size, female mating rate, fertility and fecundity. Atrazine exposure decreased the proportion pupated, the proportion emerged and adult survival. Development time was also affected by atrazine and exposed flies pupated and emerged earlier than controls. Although development time was accelerated, body size was actually larger in some of the exposures. Atrazine exposure had no effect on female mating rate and the effects on female fertility and fecundity were only observed in one of the two independent experimental blocks. Many of the traits showed non-monotonic dose response curves, where the intermediate concentrations showed the largest effects. Overall this study shows that atrazine influences a variety of life history traits in the model genetic system, D. melanogaster, and future studies should aim to identify the molecular mechanisms of toxicity.