Chromatin remodeling and Rb activity

Chromatin remodeling and Rb activity
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DOI:
10.1016/s0955-0674(00)00152-6
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发表时间:
2000-12-01
影响因子:
7.5
通讯作者:
Dean, DC
Dean, DC
中科院分区:
生物学2区
文献类型:
--
作者:
Harbour, JW;Dean, DC

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Progression of cells through the cell cycle is central to normal cell proliferation, and checkpoints that regulate this cycle are targets of tumorigenic mutations. One of these checkpoints is the Rb family of proteins that seems to regulate exit of cells from both G(1) and S phase of the cell cycle. Recent studies have linked the function of the Rb family to chromatin remodeling enzymes.