Effects of working memory deficits on the communicative functioning of Alzheimer's dementia patients
Effects of working memory deficits on the communicative functioning of Alzheimer's dementia patients
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DOI：
10.1016/s0021-9924(03)00020-0
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发表时间：
2003-05-01
影响因子：
1.7
通讯作者：
Bayles, KA
中科院分区：
文献类型：
--
作者：
Bayles, KA
阿尔茨海默病患者会经历额叶病变，工作记忆过程中的缺陷也有很好的记录。各种工作记忆缺陷是如何影响交流功能的，这方面的文献较少。本文介绍了轻度和中度阿尔茨海默病患者在五项语言理解测试和四项语言表达测试中的表现数据，并在工作记忆功能受损的情况下进行了讨论。本文认为，语言理解和语言产出测试成绩下降的主要原因是跨度能力减弱、注意力难以集中、编码和激活长期知识，而不是语言知识的丧失。学习结果：(1)读者将熟悉阿尔茨海默病患者在常见语言表达和理解任务中的典型功能。(2)读者将熟悉语言知识和表现之间的区别，以及它在理解阿尔茨海默病患者沟通障碍原因方面的重要性。(3)读者将熟悉可能促进阿尔茨海默病患者沟通功能的技术。(C)2003 Elsevier Science Inc.保留所有权利。
Individuals with Alzheimer's disease experience frontal lobe pathology and deficits in working memory processes are well documented. Less documented is how various working memory deficits impact communicative functioning. The performance data of individuals with mild and moderate Alzheimer's dementia on five tests of language comprehension and four tests of language expression are presented and discussed in the context of possible contributions from impaired working memory functions. The argument is advanced that diminished scores on tests of language comprehension and production result primarily from attenuated span capacity, difficulty focusing attention, encoding, and activation of long-term knowledge rather than from loss of linguistic knowledge. Techniques that may advantage Alzheimer's patients in the comprehension and expression of linguistic information are discussed.Learning outcomes: (1) Readers will become familiar with the typical functioning of individuals with Alzheimer's disease on common linguistic expression and comprehension tasks. (2) Readers will become familiar with the distinction between language knowledge and performance and its importance in understanding the cause of communication breakdowns in individuals with Alzheimer's disease. (3) Readers will become familiar with techniques that may facilitate the communicative functioning of individuals with Alzheimer's disease. (C) 2003 Elsevier Science Inc. All rights reserved.