New vessels detected on wide-field imaging compared to two-field and seven-field imaging: implications for diabetic retinopathy screening image analysis.
New vessels detected on wide-field imaging compared to two-field and seven-field imaging: implications for diabetic retinopathy screening image analysis.
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DOI：
10.1136/bjophthalmol-2015-306719
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发表时间：
2015-12
期刊：
影响因子：
--
通讯作者：
Taylor R
中科院分区：
文献类型：
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作者：
Talks SJ;Manjunath V;Steel DH;Peto T;Taylor R
广域视网膜成像(Optomap)用于检测糖尿病视网膜病变(DR)，已被证明可与七视野早期治疗糖尿病视网膜病变研究(ETDRS)照片相媲美。Optomap 200°图像覆盖了80%的视网膜表面，而标准的7视场30°图像覆盖了30%的视网膜表面。在英格兰，DR筛查是通过DR筛查服务(DRSS)对每只眼睛45°的两张图像进行分级进行的。为了评估在DRSS转诊的一组患者中，在DRSS之外的两个视野和标准七视野摄影中，在Optomap成像上观察到视网膜新血管(NV)的频率。从DRSS转诊为增殖前期或增殖期DR或糖尿病黄斑病变的DR患者，在转诊后3个 月内用OptomMAP彩色图像进行连续系列的治疗。记录NVS在两野和七野区域的发生率和分布。在781例患者的1562只幼稚眼中，102只眼(6.5%)出现NVS。其中72只眼被DRSS诊断为NVS，但25例患者的30只眼(占检测到的NVS的29%)被转介为较轻的DR。在报告的转诊的30只无NVS的眼中，25只眼的NVS位于DRSS标准的两个视野之外，12只眼的NVS位于七视野成像覆盖的区域之外(11.7%)。在英国DRSS推荐的患者中，使用Optomap的广域成像检测到的NV比标准的两场成像多出约30%。
Wide-field retinal imaging (Optomap), used for detecting diabetic retinopathy (DR), has been shown to compare well with seven-field early treatment diabetic retinopathy study (ETDRS) photographs. An Optomap 200° image covers 80% of the retinal surface, compared with the standard seven-field, 30° images, covering 30% of the retinal surface. In England, DR screening is performed by grading two, 45° images per eye, by the DR screening service (DRSS). To assess how often retinal new vessels (NVs) are observed on Optomap imaging, outside the DRSS two fields and standard seven-field photography, in a cohort of patients referred by the DRSS. A consecutive series of treatment naïve patients with DR, referred from DRSS with pre-proliferative or proliferative DR or diabetic maculopathy, were imaged with Optomap colour images, within 3 months of DRSS referral. The incidence and distribution of NVs were recorded in relation to two-field and seven-field areas. NVs were found in 102 of 1562 treatment naïve eyes (6.5%) of 781 patients. Of these, 72 were referred from DRSS as having NVs, but an additional 30 eyes (29% of NVs detected) from 25 patients were referred with a lesser degree of DR. In 25 of the 30 eyes without NVs reported on referral, NVs were located outside the standard two fields taken at DRSS, and in 12, NVs were outside the area covered on seven-field imaging (11.7% of eyes with NVs). Wide-field imaging with Optomap detected approximately 30% more NVs than standard two-field imaging in patients referred from a UK DRSS.