High frequency epicardial echocardiography for coronary artery evaluation: in vitro and in vivo validation of arterial lumen and wall thickness measurements.
High frequency epicardial echocardiography for coronary artery evaluation: in vitro and in vivo validation of arterial lumen and wall thickness measurements.
复制标题
用于冠状动脉评估的高频心外膜超声心动图：动脉腔和壁厚度测量的体外和体内验证。
DOI：
10.1016/s0735-1097(86)80189-9
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发表时间：
1986
影响因子：
24
通讯作者：
Kerber,RE
中科院分区：
文献类型：
--
作者：
McPherson,DD;Armstrong,M;Rose,E;Kieso,RA;Megan,M;Hunt,M;Hite,P;Marcus,ML;Kerber,RE
本研究的目的是确定一种新的高频超声心动图技术用于定量评估冠状动脉管腔和管壁尺寸的准确性。在32只开胸动物中，管腔直径的高频超声心动图测量(ECHO)与体外组织学测量(HISO)有很好的相关性(r=0.86；高频回声=0.89 HISO+0.79)(范围1.7~5.8 mm)。在体外研究的五个人类尸检心脏的评估中也发现了类似的结果。人体尸检心脏冠状动脉壁厚度与高频超声心动图测量结果具有良好的相关性(r=0.86；高频回声=0.65 HISTO+0.24)(范围0.3~0.8 mm)。在8头开胸小牛中，高频超声心动图测量总血管直径与声学测微仪测量(SONO)有很好的相关性(r=0.94；高频回声=1.03 SONO+0.4)(范围2.1-5.3 mm)。高频超声心动图测量的观察者间和观察者内变异性测量显示良好的重复性(r=0.95，壁厚观察者间变异性；r=0.97，管腔直径观察者间变异性；n=10人死后冠状动脉)。综上所述，高频超声心动图是一种准确和可重复性的测量冠脉管腔和室壁几何形状的方法，可能是一种潜在的有用的在体冠状动脉评估工具。
The purpose of this study was to determine the accuracy of a new high frequency echocardiographic technique for the quantitative assessment of coronary artery luminal and wall dimensions. In 32 open chest animals, high frequency echocardiographic measurements (echo) of luminal diameter correlated well with in vitro histologic measurements (Histo) (r = 0.86; high frequency echo = 0.89 Histo + 0.79) (range 1.7 to 5.8 mm). Similar results were found in the evaluation of five human autopsy hearts studied in vitro. Coronary artery wall thickness measurements in human autopsy hearts showed a good correlation with high frequency echocardiographic measurements (r = 0.86; high frequency echo = 0.65 Histo + 0.24) (range 0.3 to 0.8 mm). In eight open chest calves, high frequency echocardiographic measurements of total vessel diameter correlated well with sonomicrometer measurements (Sono) (r = 0.94; high frequency echo = 1.03 Sono + 0.4) (range 2.1 to 5.3 mm).Inter- and intraobserver variability measurements of high frequency echocardiographic measurements demonstrated excellent reproducibility (r = 0.95, interobserver variability for wall thickness; r = 0.97, inter-observer variability for luminal diameter; n = 10 postmortem human coronary arteries). In conclusion, high frequency echocardiography is an accurate and reproducible method of measuring coronary luminal and wall geometry and may be a potentially useful tool for in vivo coronary artery evaluation in patients.