Echocardiographic-Based Assessment of Myocardial Fiber Structure in Individual, Excised Hearts
Echocardiographic-Based Assessment of Myocardial Fiber Structure in Individual, Excised Hearts
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DOI：
10.1177/0161734612455580
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发表时间：
2012-07-01
影响因子：
2.3
通讯作者：
Holland, Mark R.
中科院分区：
文献类型：
--
作者：
Milne, Michelle L.;Singh, Gautam K.;Holland, Mark R.
本研究的目的是评估使用超声心动图成像作为确定完整个体心脏心肌纤维结构的方法的可行性。使用市售超声心动图成像系统对七个福尔马林固定的离体羊心脏进行成像，并确定距每颗心脏心尖特定距离的重建短轴横截面的内在纤维结构。采集每颗心脏的扩散张量磁共振 (DT-MR) 图像，并创建纤维图，以便与从相应的重建超声心动图图像获得的纤维结构进行比较。这两种获得纤维结构的方法显示出相对较好的一致性，表明单个心脏的纤维取向的测量可以从超声心动图图像中获得。该方法的进一步发展可能提供一种临床上有用的方法，用于绘制个体患者在心动周期中的纤维方向。
The objective of this study was to assess the feasibility of using echocardiographic imaging as an approach for determining the myocardial fiber structure of intact, individual hearts. Seven formalin-fixed, ex vivo sheep hearts were imaged using a commercially available echocardiographic imaging system, and the intrinsic fiber structure for the reconstructed short-axis cross section was determined for a specific distance from the apex of each heart. Diffusion tensor magnetic resonance (DT-MR) images of each heart were acquired and fiber maps were created for comparison with the fiber structure obtained from the corresponding reconstructed echocardiographic images. These two methods of obtaining the fiber structure showed relatively good agreement, suggesting that measurements of fiber orientation for individual hearts can be derived from echocardiographic images. Further development of this method may provide a clinically useful approach for mapping the fiber orientation in individual patients over the heart cycle.