The relationship of psychosocial factors to total mortality among older Japanese-American men: The Honolulu Heart Program
The relationship of psychosocial factors to total mortality among older Japanese-American men: The Honolulu Heart Program
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DOI：
10.1046/j.1532-5415.2001.49148.x
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发表时间：
2001-06-01
影响因子：
6.3
通讯作者：
Curb, JD
中科院分区：
文献类型：
--
作者：
Ceria, CD;Masaki, KH;Curb, JD
目的：研究心理社会因素作为全因死亡危险因素的预测价值。设计：一项以社区为基础的纵向队列研究：檀香山心脏计划。设置：在夏威夷的奥廷加进行的以人群为基础的研究。参与者：对3497名年龄在71岁至93岁的男性进行了检查，并对全因死亡率进行了平均6年的前瞻性随访。测量：使用Lubben社交网络量表（LSNS）获得心理社会数据。该量表由10个项目组成，包括家庭关系（3个项目）、与朋友的关系（3个项目）和相互依赖的社会支持和生活安排（4个项目）。我们将LSNS评分分为四分位数进行比较，第一个四分位数代表最低的社会支持，第四个四分位数代表最高的社会支持。第一个四分位数中有33.8%在随访期间死亡，第二个四分位数中有23.4%，第三个四分位数中有18%，第四个四分位数中有15.7%（P <0.001）。第一、第二、第三和第四年的6年年龄调整死亡率分别为66.2、45.7、37.8和33.7/1000人年（P <0.001）。使用年龄校正的考克斯比例风险模型，以LSNS的第一个四分位数作为参考组，死亡的相对风险为0.69（95%置信区间（CI）= 0.58-0.82），0.57在第二、第三和第四四个四分位数中分别为0.52（95%CI = 0.43-0.64）和0.47（95%CI = 0.47-0.70）。重复考克斯模型，控制年龄和吸烟状况，低LSNS评分仍然与较高的死亡率显着相关（P =.0001）。结论：我们的研究结果表明，社交网络显着独立相关的6年全因死亡率在这个队列的老年日裔美国男性。对老年人的社会干预可以降低早期死亡率。
OBJECTIVE: To examine the predictive value of psychosocial factors as risk factors for all-cause mortality.DESIGN: A community-based longitudinal cohort study: The Honolulu Heart Program.SETTING: Population-based study conducted in Oahu, Hawaii.PARTICIPANTS: Three thousand four hundred and ninety-seven men age 71 to 93 were examined and followed prospectively for all-cause mortality for an average of 6 years.MEASUREMENTS: Psychosocial data were obtained using the Lubben Social Networks Scale (LSNS). The LSNS consists of 10 items-family relationships (three items), relationships With friends (three items), and interdependent social supports and living arrangements (four items). We divided the LSNS score into quartiles for comparison, with the first quartile representing the lowest social support and the fourth quartile representing the highest social support.RESULTS: A significant dose-response relationship was noted with LSNS score and total mortality: 33.8% in the first quartile died over the follow-up period, 23.4% in the second, 18% in the third, and 15.7% in the fourth (P < .001). Six-year age-adjusted mortality rates were 66.2, 45.7, 37.8, and 33.7 per 1,000 person years in the first, second, third, and fourth, respectively (P < .001). Using age-adjusted Cox proportional hazards models, with the first quartile of LSNS as the reference group, relative risk for mortality was 0.69 (95% confidence interval (CI) = 0.58-0.82), 0.57 (95% CI = 0.47-0.70), and 0.52 (95% CI = 0.43-0.64) in the second, third, and fourth quartiles, respectively. Cox models were repeated, controlling for age and smoking status, and low LSNS scores remained significantly associated with higher mortality (P =.0001).CONCLUSIONS: Our findings suggest that social networks were significantly independently associated with 6-year all-cause mortality in this cohort of older Japanese-American men. Social interventions in old age may reduce early mortality.