Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization
Ultra-high resolution flat-panel volume CT: fundamental principles, design architecture, and system characterization
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DOI：
10.1007/s00330-006-0156-y
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发表时间：
2006-06-01
影响因子：
5.9
通讯作者：
Flohr, Thomas
中科院分区：
文献类型：
--
作者：
Gupta, Rajiv;Grasruck, Michael;Flohr, Thomas
数字平板容积CT（VCT）代表了一种独特的设计，能够实现超高空间分辨率、直接容积成像和动态CT扫描。这项创新，当充分发展，有希望打开一个独特的窗口，对人体解剖学和生理学。例如，该技术提供的体积覆盖使我们能够观察整个器官的灌注，例如脑、肝或肾，断层摄影（例如，移植或缺血事件后）。由于其较高的分辨率，人们可以直接看到骨的小梁结构。本文描述了VCT的基本设计架构。三大技术挑战，即：为了成功实施VCT扫描仪，必须解决散射校正、动态范围扩展和时间分辨率提高问题。这些问题是如何解决的VCT原型和必要的修改，使超高分辨率的体积扫描。散射校正和剂量减少的基本原则说明与实际原型的帮助。该原型的图像质量指标的特点和比较与多探测器CT（MDCT）。
Digital flat-panel-based volume CT (VCT) represents a unique design capable of ultra-high spatial resolution, direct volumetric imaging, and dynamic CT scanning. This innovation, when fully developed, has the promise of opening a unique window on human anatomy and physiology. For example, the volumetric coverage offered by this technology enables us to observe the perfusion of an entire organ, such as the brain, liver, or kidney, tomographically (e.g., after a transplant or ischemic event). By virtue of its higher resolution, one can directly visualize the trabecular structure of bone. This paper describes the basic design architecture of VCT. Three key technical challenges, viz., scatter correction, dynamic range extension, and temporal resolution improvement, must be addressed for successful implementation of a VCT scanner. How these issues are solved in a VCT prototype and the modifications necessary to enable ultra-high resolution volumetric scanning are described. The fundamental principles of scatter correction and dose reduction are illustrated with the help of an actual prototype. The image quality metrics of this prototype are characterized and compared with a multi-detector CT (MDCT).