Two decades of diabetes prevention efforts: A call to innovate and revitalize our approach to lifestyle change.

Two decades of diabetes prevention efforts: A call to innovate and revitalize our approach to lifestyle change.
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DOI:
10.1016/j.diabres.2022.110195
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发表时间:
2023-04
影响因子:
5.1
通讯作者:
Gregg, Edward W.
Gregg, Edward W.
中科院分区:
医学3区
文献类型:
--
作者:
Golovaty, Ilya;Ritchie, Natalie D.;Tuomilehto, Jaakko;Mohan, Viswanathan;Ali, Mohammed K.;Bergman, Michael;Moin, Tannaz;Gregg, Edward W.

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全球糖尿病预防工作的影响一直不大,尽管近20年前有里程碑式的糖尿病预防试验的承诺。虽然国家和区域举措显示出潜力,但在现实世界中调整适合个人及其社区的大规模战略方面仍然存在挑战。此外,在COVID-19大流行期间,久坐的生活方式发生了变化,现在的指导方针要求更早地进行筛查(例如,美国志愿工作队)将增加全球合格成年人的人数。因此,迫切需要一种更具适应性的、以人为本的方法来扩展现有的工具包,以创新和振兴我们的糖尿病预防方法。本综述基于全球转化项目专家对当前证据的共识评估,确定了优化人群水平糖尿病预防的关键优先事项;确定的关键优先事项包括(1)参与者资格,(2)干预强度,(3)交付组件,(4)行为经济学,(5)技术和(6)药物治疗的作用。我们为更广泛的以人为本的方法提供了一个概念框架,以更好地解决个人的风险,准备,障碍和数字能力。
The impact of global diabetes prevention efforts has been modest despite the promise of landmark diabetes prevention trials nearly twenty years ago. While national and regional initiatives show potential, challenges remain to adapt large-scale strategies in the real-world that fits individuals and their communities. Additionally, the sedentary lifestyle changes during the COVID-19 pandemic and guidelines that now call for earlier screening (e.g., US Preventative Task Force) will increase the pool of eligible adults worldwide. Thus, a more adaptable, person-centered approach that expands the current toolkit is urgently needed to innovate and revitalize our approach to diabetes prevention. This review identifies key priorities to optimize the population-level delivery of diabetes prevention based on a consensus-based evaluation of the current evidence among experts in global translational programs; key priorities identified include (1) participant eligibility, (2) intervention intensity, (3) delivery components, (4) behavioral economics, (5) technology, and (6) the role of pharmacotherapy. We offer a conceptual framework for a broader, person-centered approach to better address an individual’s risk, readiness, barriers, and digital competency.
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