Fix it, don't trash it: Ribosome maintenance by chaperone-mediated repair of damaged subunits.
Fix it, don't trash it: Ribosome maintenance by chaperone-mediated repair of damaged subunits.
复制标题
修复它,不要丢弃它:通过伴侣介导的受损亚基修复来维持核糖体。
DOI:
10.1016/j.molcel.2023.04.006
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发表时间:
2023
期刊:
影响因子:
16
通讯作者:
Brar,GloriaAnn
中科院分区:
文献类型:
--
作者:
Spiri,Silvan;Brar,GloriaAnn
Acute stressors or normal cellular function may result in ribosomal protein damage, which threatens the functional ribosome pool and translation. In this issue, Yang et al.1show that chaperones can extract damaged ribosomal proteins and replace them with newly synthesized versions to repair mature ribosomes.