Intestinal absorption of small peptides: a review
Intestinal absorption of small peptides: a review
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DOI：
10.1111/ijfs.14048
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发表时间：
2018-11
影响因子：
3.3
通讯作者：
Weilin Shen;T. Matsui
中科院分区：
文献类型：
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作者：
Weilin Shen;T. Matsui
多肽由于其不同的氨基酸组成而表现出不同的结构特征。结构的多样性往往赋予它们复杂的生理功能，或可能的有益健康的作用。一些小肽（二肽/三肽）对高血压、高胆固醇血症和动脉粥样硬化等疾病具有预防作用。尽管它们对健康有益，但对肽吸收的有限理解可能会阻碍它们的广泛应用。因此，本文就小肽在体外和体内的肠道吸收研究进展及影响小肽吸收的潜在因素作一综述。
Peptides display diverse structural features because of their varied amino acid compositions. The structural diversity often imparts them complex physiological functions, or possible health‐beneficial effects. Some small peptides (di‐/tripeptides) exert preventive effects against conditions such as hypertension, hypercholesterolaemia and atherosclerosis. Despite their health benefits, a limited understanding of peptide absorption may hinder their extensive application. Therefore, this review briefly introduces the in vitro and in vivo findings on the intestinal absorption of small peptides and potential factors affecting their absorption.