Role of potassium in the reflex regulation of blood pressure during static exercise in man.
Role of potassium in the reflex regulation of blood pressure during static exercise in man.
复制标题
钾在人体静态运动期间血压反射调节中的作用。
DOI：
10.1113/jphysiol.1992.sp019183
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
G. Sjøgaard
中科院分区：
文献类型：
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作者：
N. Fallentin;B. Jensen;S. Byström;G. Sjøgaard
1. 在最大自主收缩（MVC）的15%和30%静态握力收缩时，研究了静脉流出血[K+]与平均动脉血压变化之间的关系。2. 为了进一步阐明K+在血压反射调节中的重要性，我们将正常恢复的情况与在收缩停止前通过阻断前臂循环进行3分钟运动后闭塞的情况进行了比较。3. 静态运动期间和之后静脉[K+]与血压反应之间存在时间和数量上的相关性。30% MVC组平均动脉血压（MAP）为161.7 mmHg，静脉[K+]为5.8 mM， 15% MVC组分别为121.5 mmHg和5.0 mM。在闭塞期，平均动脉血压保持高于静息水平，并提供了肌肉化学反射幅度的测量。同一时期，30% MVC和15% MVC分别维持静脉[K+]在5.3 mM和4.6 mM。这表明间质浓度高于8 - 10 mM。这一水平足以刺激参与血压反射调节的III型和IV型肌肉传入神经，并加强了K+可能在引发加压反射中发挥重要作用的概念。5. 与[K+]相反，静脉血乳酸和氨（NH3）浓度的时间过程与血压记录明显分离。
1. The relationship between [K+] in venous effluent blood and alterations in mean arterial blood pressure was studied during static handgrip contractions at 15 and 30% of maximal voluntary contraction (MVC). 2. To further elucidate the importance of K+ in the reflex regulation of blood pressure a situation with normal recovery was compared with a situation in which 3 min of post‐exercise occlusion was applied by arresting the circulation to the forearm just prior to the cessation of the contraction. 3. There was a temporal as well as quantitative correlation between venous [K+] and the blood pressure response during and after static exercise. During 30% MVC mean arterial blood pressure (MAP) attained 161.7 mmHg and venous [K+] 5.8 mM, while the corresponding values during 15% MVC were 121.5 mmHg and 5.0 mM. 4. In the occlusion period mean arterial blood pressure remained elevated above resting level and provided a measure of the magnitude of muscle chemoreflexes. In the same period venous [K+] was maintained at 5.3 mM and 4.6 mM following 30% MVC and 15% MVC respectively. This is indicative of interstitial concentrations of above 8‐10 mM. This level is sufficiently high to stimulate type III and IV muscle afferents involved in the reflex regulation of blood pressure, and strengthens the notion that K+ may play an important role in eliciting the pressor reflex. 5. In contrast to [K+] the time course of venous blood concentrations of lactate and ammonia (NH3) exhibited a clear dissociation from the blood pressure recordings.
股薄肌间质钾浓度的增加会刺激第 III 组和第 IV 组传入神经。
DOI：
10.1152/jappl.1985.58.3.936
发表时间：
1985
期刊：
Journal of applied physiology (Bethesda, Md. : 1985)
影响因子：
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作者：
Rybicki,KJ;Waldrop,TG;Kaufman,MP
通讯作者：
Kaufman,MP