Brain network connectivity-behavioral relationships exhibit trait-like properties: Evidence from hippocampal connectivity and memory.
Brain network connectivity-behavioral relationships exhibit trait-like properties: Evidence from hippocampal connectivity and memory.
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DOI：
10.1002/hipo.22480
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发表时间：
2015-12
期刊：
影响因子：
3.5
通讯作者：
Dickerson BC
中科院分区：
文献类型：
--
作者：
Touroutoglou A;Andreano JM;Barrett LF;Dickerson BC
尽管越来越多的研究表明行为和静息状态下功能性MRI测量的大规模大脑网络连接之间的关系，但据我们所知，还没有研究试图调查内在连接-行为关系是否随时间而稳定。在这项研究中，我们在两个时间点（大约间隔1周）研究了这种大脑行为关系的稳定性。我们重点研究了海马与后扣带回皮质的连接强度与情景记忆表现之间的关系。我们的研究结果表明，这种关系在不同年龄的样本中是稳定的，并且在两个时间点上是可靠的。这些发现提供了第一个证据，证明大规模内在网络连接和情景记忆表现之间的关系是一个稳定的特征，个体之间存在差异。
Despite a growing number of studies showing relationships between behavior and resting-state functional MRI measures of large-scale brain network connectivity, no study to our knowledge has sought to investigate whether intrinsic connectivity-behavioral relationships are stable over time. In this study, we investigated the stability of such brain-behavior relationships at two timepoints, approximately 1 week apart. We focused on the relationship between the strength of hippocampal connectivity to posterior cingulate cortex and episodic memory performance. Our results showed that this relationship is stable across samples of a different age and reliable over two points in time. These findings provide the first evidence that the relationship between large-scale intrinsic network connectivity and episodic memory performance is a stable characteristic that varies between individuals.