Percutaneous CT-guided fine-needle aspiration of pulmonary lesions: Results and complications in 409 patients
Percutaneous CT-guided fine-needle aspiration of pulmonary lesions: Results and complications in 409 patients
复制标题
DOI：
10.1111/j.1440-1673.2008.01990.x
复制
发表时间：
2008-10-01
影响因子：
1.6
通讯作者：
Andreou, J.
中科院分区：
文献类型：
--
作者：
Laspas, F.;Roussakis, A.;Andreou, J.
本研究的目的是报告我们中心在经皮CT引导下肺活检的结果和并发症方面的经验。回顾性分析了409例5年多来接受经皮CT引导下细针抽吸肺部可疑病变的患者。结节大小范围为0.6至10 cm。使用的针头口径为21-23 G。评价标本充分性和患者结局。对每个病例进行了并发症审查。在409例细针穿刺中，369例（90%）获得了足够的诊断材料。290例（70%）样本诊断为恶性肿瘤，4例（1%）样本可疑为恶性肿瘤，65例（16%）样本为恶性肿瘤阴性，10例（3%）样本中确定为良性结果。假阴性25例，假阳性1例。敏感性为92%，特异性为98%。气胸是最常见的并发症，有17例（4%）患者发生。其中只有1例需要胸腔引流。8例（2%）患者活检后CT检查发现病变周围或沿着针道有血液渗出。然而，其中只有一人有轻度咯血。CT引导下经皮肺穿刺活检是一种快速、有效的诊断方法，并发症发生率低。
The purpose of this study was to report our centre's experience in the results and complications of percutaneous CT-guided lung biopsy. A retrospective review of 409 patients who underwent percutaneous CT-guided fine-needle aspiration of suspicious lung lesions for more than 5 years was carried out. Nodule sizes ranged from 0.6 to 10 cm. The calibre of the needle used was 21-23 G. Specimen adequacy and patient outcome were evaluated. Each case was reviewed for complications. Sufficient diagnostic material was obtained in 369 (90%) of the 409 fine-needle aspirations. Diagnosis was malignancy in 290 (70%) samples, four (1%) samples were suspicious for malignancy, 65 (16%) samples were negative for malignancy and definite benign findings were identified in 10 (3%) specimens. There were 25 false-negative cases and one false-positive case. Sensitivity was 92% and specificity 98%. Pneumothorax was the most common complication and occurred in 17 (4%) patients. Only one of them required thoracic drainage. Blood effusion around the lesion or along the needle track was detected on the post-biopsy CT in 8 (2%) patients. However, only one of them suffered from a mild haemoptysis. Percutaneous CT-guided biopsy is an effective and fast procedure for diagnosis of suspected pulmonary malignancy, with a low complication rate.