Circulatory responses to stimulation of left ventricular receptors in the cat.
Circulatory responses to stimulation of left ventricular receptors in the cat.
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猫对左心室受体刺激的循环反应。
DOI：
10.1111/j.1748-1716.1973.tb05429.x
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发表时间：
1973
期刊：
影响因子：
--
通讯作者：
P. Thoren
中科院分区：
文献类型：
--
作者：
B. Oberg;P. Thoren
在氯醛糖麻醉的猫身上，通过短暂的主动脉阻断或心包内注射尼古丁，可刺激非延髓迷走神经传入的左心室感受器放电。观察对心率、肾脏和骨骼肌阻抗血管和肌肉电容血管的诱发反射效应，并与动脉压力感受器刺激的反射效应进行比较。刺激脑室受体引起相当大的心率减慢，这几乎完全是由于迷走神经的激活，以及肾脏和肌肉阻力血管以及肌肉电容血管的反射性扩张。对于具有两种反射机制的骨骼肌血流阻力的给定反射性降低，刺激脑室感受器时伴随的反射性心动过缓和肾血管扩张比激活动脉压力感受器时更明显。然而，两个受体组的电容血管似乎以相同的程度接合。在脑室受体激活后，反射性肌肉扩张完全是由于肾上腺素能血管收缩纤维活动的抑制，而没有任何胆碱能血管扩张纤维激活的证据。
Left ventricular receptors, firing in non-medullated vagal afferents, were stimulated in chloralose-anesthetized cats by brief aortic occlusions or by intrapericardial injections of nicotine. The induced reflex effects on heart rate, renal and skeletal muscle resistance vessels and muscle capacitance vessels were followed and compared with the reflex effects of arterial baroreceptor stimulation. Stimulation of the ventricular receptors induced a considerable reduction in heart rate, almost entirely due to vagal activation, and to a reflex dilatation of renal and muscle resistance vessels and of the muscle capacitance vessels. For a given reflex reduction of skeletal muscle flow resistance with the two reflex mechanisms, the concomitant reflex bradycardia and renal vasodilatation was more pronounced when the ventricular receptors were stimulated than upon activation of the arterial baroreceptors. The capacitance vessels seemed, however, to be engaged to the same extent from the two receptor groups. The reflex muscle dilatation, following ventricular receptor activation, was solely due to inhibition of adrenergic vasoconstrictor fibre activity with no evidence of any cholinergic vasodilator fibre activation.