A comparison of disease susceptibility and innate immune response between diploid and triploid Atlantic salmon (Salmo salar) siblings following experimental infection with Neoparamoeba perurans, causative agent of amoebic gill disease.
A comparison of disease susceptibility and innate immune response between diploid and triploid Atlantic salmon (Salmo salar) siblings following experimental infection with Neoparamoeba perurans, causative agent of amoebic gill disease.
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DOI：
10.1017/s0031182017000622
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发表时间：
2017-08
期刊：
影响因子：
2.4
通讯作者：
Adams A
中科院分区：
文献类型：
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作者：
Chalmers L;Taylor JF;Roy W;Preston AC;Migaud H;Adams A
很少有研究集中在三倍体大西洋鲑鱼的健康和免疫力上，因此，关于它们对具有商业意义的病原体的反应仍然知之甚少。如果要考虑将三倍体库存用于全面的商业生产，这一点很重要。本研究旨在研究和比较三倍体和二倍体大西洋鲑鱼对阿米巴鳃病(AGD)病原体新阿米巴的攻击反应。这种疾病对水产养殖业具有重大的经济意义。结果表明，倍性对鳃大体评分和鳃细丝的影响不显著，而感染和时间有显著影响。倍性、感染和时间不影响补体或抗蛋白酶活性。倍性在感染后21天对溶菌酶活性有显著影响(而感染和时间不影响)，尽管活性在以前记录的鲑鱼范围内。库存对所测量的任何参数都没有显著影响。根据研究结果，可以认为，倍性不影响AGD病理的表现或严重程度，也不影响血清天然免疫反应。此外，二倍体和三倍体大西洋鲑鱼的血清免疫反应可能不会受到阿米巴鳃病的显著影响。
Few studies have focussed on the health and immunity of triploid Atlantic salmon and therefore much is still unknown about their response to commercially significant pathogens. This is important if triploid stocks are to be considered for full-scale commercial production. This study aimed to investigate and compare the response of triploid and diploid Atlantic salmon to an experimental challenge with Neoparamoeba perurans, causative agent of amoebic gill disease (AGD). This disease is economically significant for the aquaculture industry. The results indicated that ploidy had no significant effect on gross gill score or gill filaments affected, while infection and time had significant effects. Ploidy, infection and time did not affect complement or anti-protease activities. Ploidy had a significant effect on lysozyme activity at 21 days post-infection (while infection and time did not), although activity was within the ranges previously recorded for salmonids. Stock did not significantly affect any of the parameters measured. Based on the study results, it can be suggested that ploidy does not affect the manifestation or severity of AGD pathology or the serum innate immune response. Additionally, the serum immune response of diploid and triploid Atlantic salmon may not be significantly affected by amoebic gill disease.