Comparison of various methods for quantification of apparent diffusion coefficient of head and neck lesions with HASTE diffusion-weighted MR imaging

Comparison of various methods for quantification of apparent diffusion coefficient of head and neck lesions with HASTE diffusion-weighted MR imaging
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DOI:
10.1016/j.oooo.2012.03.015
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发表时间:
2012-08-01
影响因子:
2.9
通讯作者:
Sano, Tsukasa
Sano, Tsukasa
中科院分区:
医学4区
文献类型:
--
作者:
Sakamoto, Junichiro;Sasaki, Yoshinori;Sano, Tsukasa

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目标.本回顾性研究的目的是比较在半傅立叶单次激发快速自旋回波(HASTE)弥散加权成像(DWI)中测量头颈部病变表观扩散系数(ADC)的各种方法,并确定预测恶性肿瘤的ADC阈值。回顾性分析46个病灶(10个囊肿,14个良性肿瘤,22个恶性肿瘤)的HASTE DW图像。比较0-1000法、500-1000法和加权线性回归(WLR)拟合法的ADC值。当ADC值为1.24 x 10(-3)mm(2)/s时,获得了83.3%、86.1%和88.9%的最高总体准确性阈值分别采用0-1000法、0.98 x 10(-3)mm(2)/s(500-1000法)和1.23 x 10(-3)mm(2)/s(WLR拟合)。本研究结果表明,ADC值与HASTE DWI测量是有用的预测头颈部病变的恶性。(Oral外科口腔医学口腔病理学口腔放射学2012;114:266-276)
Objectives. The purposes of this retrospective study were to compare various methods of apparent diffusion coefficient (ADC) measurement for head and neck lesions in half-Fourier single-shot turbo spin-echo (HASTE) diffusion-weighted imaging (DWI) and determine the threshold ADC value for predicting malignancy.Study Design. HASTE DW images of 46 lesions (10 cysts, 14 benign tumors, and 22 malignant tumors) were studied retrospectively. The ADC values were compared among the 0-1000 method, 500-1000 method, and weighted linear regression (WLR) fit.Results. The highest overall accuracies of 83.3%, 86.1%, and 88.9% were obtained when ADC values of 1.24 x 10(-3) mm(2)/s (0-1000 method), 0.98 x 10(-3) mm(2)/s (500-1000 method), and 1.23 x 10(-3) mm(2)/s (WLR fit), respectively, were used for the threshold.Conclusions. The present results indicate that ADC measurement with HASTE DWI is useful in predicting malignancy of head and neck lesions. (Oral Surg Oral Med Oral Pathol Oral Radiol 2012;114:266-276)