Exposure to electromagnetic fields and risk of central nervous system disease in utility workers
Exposure to electromagnetic fields and risk of central nervous system disease in utility workers
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DOI：
10.1097/00001648-200009000-00009
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发表时间：
2000-09-01
期刊：
影响因子：
5.4
通讯作者：
Johansen, C
中科院分区：
文献类型：
--
作者：
Johansen, C
职业暴露在电磁场中与神经疾病有关，如肌萎缩侧索硬化症、老年痴呆症、帕金森病和阿尔茨海默病，我研究了1900至1993年间在丹麦公用事业公司工作的30,631名员工的中枢神经系统疾病的发病率。我将队列与以人口为基础的全国丹麦国家患者登记表联系起来，并将1978年至1993年观察到的这些疾病的病例数量与普通人口中的相应比率进行了比较。此外，我对公用事业工人的数据进行了拟合，建立了与估计的50赫兹电磁场暴露水平有关的乘法泊松回归模型。总体而言，电视增加了老年痴呆症和运动神经元疾病的风险。帕金森病、阿尔茨海默病和其他中枢神经系统疾病的发病率基本上与暴露在电磁场中无关。与普通人群相比，癫痫风险的降低可能反映了健康工作者的效应；我观察到，基于内部比较，癫痫风险增加。老年痴呆症和运动神经元疾病风险的增加可能与暴露在电磁场中的高于平均水平有关。
Occupational exposure to electromagnetic fields has been associated with neurological diseases such as amyotrophic lateral sclerosis, senile dementia, Parkinson disease, and Alzheimer disease, I studied the incidence of central nervous system diseases in 30,631 persons employed in Danish utility companies between 1900 and 1993. I linked the cohort to the nationwide, population-based Danish National Register of Patients and compared the numbers of cases of these diseases observed between 1978 and 1993 with the corresponding rates in the general population. In addition I fit to the data on utility workers a multiplicative Poisson regression model in relation to estimated levels of exposure to 50-Hz electromagnetic fields. Overall, there tvas an increase in risk for senile dementia and motor neuron diseases combined. The incidences of Parkinson disease, Alzheimer disease, and other diseases of the central nervous system were essentially unrelated to exposure to electromagnetic fields. A decreased risk of epilepsy compared with the general population probably reflects a healthy worker effect; I observed an increased risk of epilepsy based on internal comparisons. The increased risk for senile dementia and motorneuron diseases may be associated with above-average levels of exposure to electromagnetic fields.