Antigenic relationships of group A arboviruses by plaque reduction neutralization testing.
Antigenic relationships of group A arboviruses by plaque reduction neutralization testing.
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通过噬菌斑减少中和测试确定 A 组虫媒病毒的抗原关系。
DOI：
10.4269/ajtmh.1975.24.527
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发表时间：
1975
期刊：
影响因子：
--
通讯作者：
N. Karabatsos
中科院分区：
文献类型：
--
作者：
N. Karabatsos
采用高度特异性的超免疫小鼠腹水和抗血清，通过空斑减少中和试验，评估了20种A组虫媒病毒的抗原关系。证实了A组病毒的三种复合物的存在。除极少数例外情况外，仅在同一复合物中的病毒中观察到异源中和反应;然而，每种复合物中至少有一种或两种免疫试剂在该复合物内具有广泛的交叉反应性。
Antigenic relationships of 20 group A arboviruses were assessed by the plaque reduction neutralization test, using highly specific hyperimmune mouse ascitic fluids and antisera. The existence of three complexes of group A viruses was verified. With rare exceptions, heterologous neutralization reactions were observed only among viruses in the same complex; however there were at least one or two immune reagents in each complex which were broadly cross-reactive within that complex.