The impact of childhood cancer: Perceptions of adult survivors.
The impact of childhood cancer: Perceptions of adult survivors.
复制标题
儿童癌症的影响：成年幸存者的看法。
作者：
Willard,VictoriaW;Klosky,JamesL;Li,Chenghong;Srivastava,DeoKumar;Brinkman,TaraM;Robison,LeslieL;Hudson,MelissaM;Phipps,Sean
研究背景本研究的目的是描述儿童癌症成年幸存者对癌症影响功能结果的看法和相关风险因素，包括社会关系、锻炼、财务和宗教。（平均年龄：32.5岁;范围：18.3 - 63.8岁;诊断后24.1年; 50.8%为男性; 84.9%为白人）。使用简明癌症影响评估（BCIA）评估对癌症影响的感知。回归模型用于评估功能结局的风险因素。BCIA的中位反应是癌症对评估领域影响最小的看法。约33.1%-46.6%的存活者在4个分量表中表示这种反应，尽管反应范围从非常积极到非常消极。除了诊断（脑肿瘤的幸存者通常表明癌症的负面影响更大，子量表估计值为-1.25对于经济和社会和情感，-1.01对于运动和饮食，比值比为1.83），大多数变异性是由于人口统计学因素，包括性别，年龄，种族，教育，结论：目前的研究结果强调，许多长期的成年幸存者认为儿童癌症对成年功能方面的影响很小，包括生活，财务，锻炼，社会情感关系和宗教。这表明幸存者可能没有关注他们的疾病在日常生活中可能造成的身体和心理晚期影响。对于那些确实感受到负面影响的人来说，反应的变化表明，有一些幸存者可能会受益于专注于实现功能目标的干预措施。
BACKGROUNDThe objective of this study was to describe perceptions and associated risk factors of the impact of cancer on functional outcomes, including social relationships, exercise, finances, and religion, among adult survivors of childhood cancer.METHODSEvaluable participants included 3001 adult survivors (mean age, 32.5 years; range, 18.3‐63.8 years; 24.1 years from diagnosis; 50.8% male; 84.9% Caucasian) who were enrolled in the St. Jude Lifetime Cohort study. Perceptions of the impact of cancer were assessed using the Brief Cancer Impact Assessment (BCIA). Regression models were used to evaluate risk factors for functional outcomes.RESULTSThe median response on the BCIA was a perception that cancer had minimal impact on the domains assessed. Approximately 33.1% to 46.6% of survivors indicated this response across the 4 subscales, although responses ranged from very positive to very negative impact. Other than diagnosis (with survivors of brain tumors generally indicating a more negative impact of cancer, with subscale estimates of −1.25 for caregiving and finance and −1.01 for social and emotional and an odds ratio of 1.83 for exercise and diet), most variability was because of demographic factors, including sex, age, race, education, and employment.CONCLUSIONSThe current findings highlight that many long‐term adult survivors perceive minimal impact of childhood cancer on functional aspects of adulthood, including caregiving, finances, exercise, social‐emotional relationships, and religion. This suggests that survivors may not be focusing on the influence of likely physical and psychological late effects of their disease in their day‐to‐day lives. For those who do perceive a negative impact, variability in responses suggests that there are of survivors who may benefit from interventions focused on the achievement of functional goals.Cancer2017;123:1625–1634.©2017 American Cancer Society.