Oxygen Plasma Treatment on 3D-Printed Chitosan/Gelatin/Hydroxyapatite Scaffolds for Bone Tissue Engineering.
Oxygen Plasma Treatment on 3D-Printed Chitosan/Gelatin/Hydroxyapatite Scaffolds for Bone Tissue Engineering.
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用于骨组织工程的 3D 打印壳聚糖/明胶/羟基磷灰石支架的氧等离子体处理。
DOI：
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发表时间：
2017
影响因子：
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通讯作者：
Byung
中科院分区：
文献类型：
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作者：
Chang;S. Yang;Sang‐Chul Jung;Byung
采用3D打印技术制备了三维羟基磷灰石/明胶/壳聚糖复合支架。用氧等离子体处理支架，提高其生物活性，并对其进行表面表征和体外细胞培养。支架具有良好的孔隙率和孔的连通性。氧等离子体刻蚀后，支架表面的粗糙度和润湿性增加。经等离子体处理的支架比未处理的支架具有更高的增殖能力。氧等离子体处理可以作为一种潜在的工具来提高三维复合支架的生物相容性。
The 3D hydroxyapatite/gelatin/chitosan composite scaffolds were fabricated by 3D printing technique. The scaffolds were treated by oxygen plasma to improve the bioactivity and its surface characterization and in vitro cell culture were investigated. The scaffolds exhibited the good porosity and interconnectivity of pores. After oxygen plasma etching, roughness and wettability on the scaffolds surface are increased. Plasma treated scaffolds showed higher proliferation than that of untreated scaffolds. Oxygen plasma treatment could be used as potential tool to enhance the biocompatibility on the 3D composite scaffolds.