Fatal hypertensive crisis as presentation of mitochondrial complex I deficiency

Fatal hypertensive crisis as presentation of mitochondrial complex I deficiency
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DOI:
10.1055/s-2007-985903
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发表时间:
2007-06-01
期刊:
影响因子:
1.4
通讯作者:
Hoehn, T.
Hoehn, T.
中科院分区:
医学4区
文献类型:
--
作者:
Lohmeier, K.;Distelmaier, F.;Hoehn, T.

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Complex I deficiency is a frequent defect of the mitochondrial electron transport chain. We report on a 3-year-old boy, who rapidly deteriorated after sudden flushing and collapse. This fatal and unusual case was characterized by widely uncontrollable arterial hypertension. It might indicate that hypertensive crisis could be a potential manifestation of mitochondrial disorders.