PREVALENCE OF NEUTRALIZING ANTIBODIES TO BOVID HERPESVIRUS 2 IN AFRICAN WILDLIFE
PREVALENCE OF NEUTRALIZING ANTIBODIES TO BOVID HERPESVIRUS 2 IN AFRICAN WILDLIFE
复制标题
非洲野生动物中牛疱疹病毒 2 型中和抗体的流行情况
DOI：
10.7589/0090-3558-18.4.429
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
R. Hedger
中科院分区：
文献类型：
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作者：
C. Hamblin;R. Hedger
1963年至1980年间，从9个非洲国家的45种不同野生动物中收集了总共3，470份血清，检测了牛疱疹病毒2型的病毒中和（VN）抗体。在20个物种中证实了抗体，包括15个牛科、2个猪科、河马（Hippopotamus amphibius）、长颈鹿（Giraffa camelopardalis）和一个绿色猴（Cercopithecus aethiops）;其中11个物种先前未记录为血清阳性。虽然在没有病毒分离的情况下中和抗体的意义仍然存在疑问，但结果表明感染在野生动物中广泛存在。结果表明，在水羚中，VN滴度最高的是椭圆羚（Kobusellipsiprymnus）和白羚（K. defassa）、苇羚（Redunca arundinum）和布法罗（Syncerus caffer）。在自由生活的布法罗群体中，感染似乎是连续的，大多数动物在2岁以前就存在抗体。
A total of 3,470 sera, collected between 1963 and 1980 from 45 different species of wildlife in nine African countries, was examined for virus neutralizing (VN) antibodies to bovid herpesvirus 2. Antibodies were demonstrated in 20 species including 15 Bovidae, two Suidae, hippopotamus (Hippopotamus amphibius), giraffe (Giraffa camelopardalis) and a green monkey (Cercopithecus aethiops); 11 of these species had not been previously recorded as sero-positive. Although the significance of neutralizing antibodies in the absence of virus isolation remains in doubt, results suggest that infection is widespread in wildlife. The highest VN titres were recorded in waterbuck (Kobus ellipsiprymnus and K. defassa), reedbuck (Redunca arundinum) and buffalo (Syncerus caffer). Infection appears to be continuous in free-living populations of buffalo and antibodies are present in the majority of animals by the age of 2 yr.