Primary liver abscess due to Klebsiella pneumoniae in Taiwan
Primary liver abscess due to Klebsiella pneumoniae in Taiwan
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DOI：
10.1086/516369
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发表时间：
1998-06-01
影响因子：
11.8
通讯作者：
Lin, HH
中科院分区：
文献类型：
--
作者：
Wang, JH;Liu, YC;Lin, HH
化脓性肝脓疡是腹腔内或胆道感染的一种罕见并发症，通常是一种与高死亡率和高复发率相关的多种微生物感染。然而，在过去的15年里，我们在台湾观察到一种新的临床综合征：由单一微生物肺炎克雷伯氏菌引起的肝脏疾病。1990年9月至1996年6月，我院共收治化脓性肝脓肿182例，其中160例为克雷伯菌感染。肺炎，22例为多种微生物。当K.肺炎性肝脓肿与多菌性肝脓肿相比，糖尿病或葡萄糖耐受不良的发生率更高（75%对4.5%）和转移性感染前者腹腔内异常率（0.6% vs. 95.5%）、死亡率（11.3% vs. 41%）和复发率（4.4% vs. 41%）较低。克雷伯氏菌引起的肝脓肿。肺炎是一种新的临床综合征，已成为台湾糖尿病患者的重要感染并发症。
Pyogenic liver abscess is an uncommon complication of intra-abdominal or biliary tract infection and is usually a polymicrobial infection associated with high mortality and high rates of relapse. However, over the past 15 years, we have observed a new clinical syndrome in Taiwan: liver abscesses caused by a single microorganism, Klebsiella pneumoniae. We reviewed 182 cases of pyogenic liver abscess during the period September 1990 to June 1996; 160 of these cases were caused by K. pneumoniae alone, and 22 were polymicrobial. When patients with K. pneumoniae liver abscess were compared with those who had polymicrobial liver abscess, we found higher incidences of diabetes or glucose intolerance (75% vs. 4.5%) and metastatic infections (11.9% vs. 0) and lower rates of intra-abdominal abnormalities (0.6% vs. 95.5%), mortality (11.3% vs. 41%), and relapse (4.4% vs. 41%) in the former group. Liver abscess caused by K. pneumoniae is a new clinical syndrome that has emerged as an important infectious complication in diabetic patients in Taiwan.