THE VALUE OF DECOMPRESSION FOR ACUTE EXPERIMENTAL SPINAL-CORD COMPRESSION INJURY

THE VALUE OF DECOMPRESSION FOR ACUTE EXPERIMENTAL SPINAL-CORD COMPRESSION INJURY
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DOI:
10.3171/jns.1980.53.6.0749
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发表时间:
1980-01-01
影响因子:
4.1
通讯作者:
ENDRENYI, L
ENDRENYI, L
中科院分区:
医学1区
文献类型:
--
作者:
DOLAN, EJ;TATOR, CH;ENDRENYI, L

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采用夹压法造成大鼠急性脊髓压迫伤。脊髓压迫的力量和持续时间是独立变化的,并使用斜面技术评估脊髓的功能恢复。数学建模产生了一条曲线,定义了受伤后每周的力、持续时间和功能恢复之间的关系。该研究清楚地表明了减压的有益效果,增加压迫力或持续时间,或两者兼而有之,会导致恢复减少。
A clip compression method was used to produce acute spinal cord compression injury in rats. The force and duration of the spinal cord compression were independently varied, and functional recovery of the cord was assessed using the inclined plane technique. Mathematical modeling produced a curve defining the relationship between force, duration and functional recovery for each week after injury. The study clearly showed the beneficial effect of decompression and that, increasing either the force or duration of compression, or both, caused a reduction in recovery.