Epidemiological and clinical profiles of acute invasive diarrhoea with special reference to mucoid episodes: A rural community-based longitudinal study
Epidemiological and clinical profiles of acute invasive diarrhoea with special reference to mucoid episodes: A rural community-based longitudinal study
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DOI：
10.1016/s0035-9203(96)90315-6
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发表时间：
1996-09-01
影响因子：
2.2
通讯作者：
Saha, NC
中科院分区：
文献类型：
--
作者：
Gupta, DN;Sircar, BK;Saha, NC
1992年8月至1994年12月，在印度加尔各答附近的3个村庄进行了一项研究，共有5464人。前瞻性观察了一组4岁以下的农村儿童，以确定粘液性腹泻的临床流行病学方面，并检查侵袭倾向。总体而言，腹泻的发病率为1.7次/儿童/年，粘液性和血性痢疾的发病率分别为0.8次和0.2次/儿童/年。6 - 11个月的儿童粘液性腹泻发病率较高（1.3次/儿童/年），高峰期发生在6月和7月。多因素logistic回归分析显示，粘液性腹泻和血性痢疾在临床和实验室表现上非常相似，包括粪便白细胞计数升高（> 10/高倍镜视野[hpf]）。然而，腹痛发生更频繁的血性痢疾比粘液性腹泻。因此，粪便白细胞计数（> 10/hpf）可用作社区水平粘液性腹泻侵袭性的指标。
A study was carried out in 3 villages near Calcutta, India, having a population of 5464, between August 1992 and December 1994. A cohort of rural children below 4 years of age was prospectively observed to determine the clinico-epidemiological aspects of mucoid diarrhoea and examine propensity to invasiveness. Overall, the incidence of diarrhoea was 1.7 episodes/child/year, and that of mucoid and bloody dysentery was 0.8 and 0.2 episodes/child/year, respectively. Children aged 6 - 11 months had a higher incidence of mucoid diarrhoea (1.3 episodes/child/year) and the peak season occurred in June and July. Multivariate analysis using logistic regression showed that mucoid diarrhoea and bloody dysentery were closely similar in both clinical and laboratory findings, including raised faecal leucocyte count (> 10/high power microscope field [hpf]). However, abdominal pain occurred more frequently in bloody dysentery than in mucoid diarrhoea. Faecal leucocyte count (> 10/hpf) can therefore be used as an indicator for invasiveness of mucoid diarrhoea at the community level.