Long-term health-related quality of life in bariatric surgery patients: A systematic review and meta-analysis
Long-term health-related quality of life in bariatric surgery patients: A systematic review and meta-analysis
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DOI：
10.1002/oby.21322
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发表时间：
2016-01-01
期刊：
影响因子：
6.9
通讯作者：
Twells, Laurie K.
中科院分区：
文献类型：
--
作者：
Driscoll, Shannon;Gregory, Deborah M.;Twells, Laurie K.
减肥手术导致大多数患者体重显著减轻。健康相关生活质量（HRQoL）的改善是一个同样重要的结局;然而，很少有研究报告长期（5年）HRQoL结局。本研究评估了HRQoL 5 years.MethodsPubMed，科克伦审查，EmBase，CINANL，PsycInfo，肥胖会议摘要和参考文献列表的证据质量和手术的有效性进行了搜索。关键词为减肥手术、肥胖和生活质量。如果（1）有5年随访，（2）患者有II或III级肥胖，（3）个体完成了有效的HRQoL调查，（4）有肥胖的非手术对照组，则纳入研究。两名审查独立评估每个study.ResultsFrom 1376篇文章中，9项研究被纳入系统评价（SR）和6在荟萃分析（MA）。与此相反，MA发现显着改善这些领域5 years after surgery.ConclusionsStudy findings提供了证据，有利于手术组的身体和心理健康的实质性和显着改善与控制跨越5至25年手术后。
ObjectiveBariatric surgery results in significant weight loss in the majority of patients. Improvement in health-related quality of life (HRQoL) is an equally important outcome; however, there are few studies reporting long-term (5 years) HRQoL outcomes. This study assesses the quality of evidence and effectiveness of surgery on HRQoL5 years.MethodsPubMed, Cochrane Review, EmBase, CINANL, PsycInfo, obesity conference abstracts, and reference lists were searched. Keywords were bariatric surgery, obesity, and quality of life. Studies were included if (1) there was 5 years follow-up, (2) patients had class II or III obesity, (3) individuals completed a validated HRQoL survey, and (4) there was a nonsurgical comparison group with obesity. Two reviewers independently assessed each study.ResultsFrom 1376 articles, 9 studies were included in the systematic review (SR) and 6 in the meta-analysis (MA). Inconsistent results for long-term improvements in physical and mental health emerged from the SR. In contrast, the MA found significant improvements in these domains 5 years after surgery.ConclusionsStudy findings provide evidence for a substantial and significant improvement in physical and mental health favoring the surgical group compared with controls spanning 5 to 25 years after surgery.