Microbial Ecology of the Human Skin
Microbial Ecology of the Human Skin
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DOI：
10.1007/s00248-016-0789-6
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发表时间：
2018-07-01
影响因子：
3.6
通讯作者：
Cundell, Anthony M.
中科院分区：
文献类型：
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作者：
Cundell, Anthony M.
这篇关于皮肤微生物群的综述文章是为了回应人类微生物组计划的结果，从培养方法过渡到细菌和真菌基因的PCR扩增和测序的最新进展。这种转变使得能够调查栖息在人类皮肤上的微生物的全部多样性。皮肤提供了一系列具有与皮肤的三个主要区域相关的不同微生物群的栖息地，即潮湿的腋窝、会阴和趾蹼;油性或皮脂腺的头部、颈部和躯干;以及干燥的前臂和腿部。这些新的独立于培养物的工具揭示了人体皮肤微生物群在身体不同部位和皮肤深度的多样性。这些工具应该有助于更好地了解微生物群与宿主之间的稳态状态以及微生物群的整体功能。
This review article on the skin microbiota was written in response to recent advances that transitioned from culture methods to PCR amplification and sequencing of bacterial and fungal genes as a result of the Human Microbiome Project. This transition enables the investigation of the full diversity of microorganisms inhabiting human skin. The skin provides a range of habitats with different microbiota associated with the three major regions of the skin, namely the moist axilla, perineum, and toe webs; oily or sebaceous head, neck, and trunk; and dry forearms and legs. These new culture-independent tools are revealing the diversity of the human skin microbiota in the different locations of the body and with skin depth. These tools should lead to a better understanding of the state of homeostasis between the microbiota and the host and the overall functionality of that microbiota.