Developmental transitions among affective and behavioral disorders in adolescent boys

Developmental transitions among affective and behavioral disorders in adolescent boys
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DOI:
10.1111/j.1469-7610.2005.00422.x
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发表时间:
2005-11-01
影响因子:
7.6
通讯作者:
Rathouz, PJ
Rathouz, PJ
中科院分区:
医学1区
文献类型:
--
作者:
Burke, JD;Loeber, R;Rathouz, PJ

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背景资料:本文扩展了最近的努力,推进超越检查并发症之间的情感和行为障碍的发展序列之间的障碍。这样做可以改进理论的测试,例如Capaldi和Patterson的行为障碍(CD)和抑郁症的失败模型。此外,对立违抗性障碍(ODD)很少被认为与CD有明显区别,这使得识别行为障碍中不同影响的能力最小化。研究方法:本文使用了来自发展趋势研究的数据,该研究是一项由177名男孩及其父母组成的临床参考队列,沿着,他们定期使用结构化临床访谈和一套全面的其他措施进行评估。男孩在7至12岁时被招募,每年重新评估,直到18岁。预测回归模型测试了疾病之间的连续性,抑郁症,过度焦虑症,注意缺陷多动障碍(ADHD),ODD和CD分别作为结果进行了检查。结果:每种疾病都表现出同型连续性,但也出现了明显的异型连续性发展序列。ADHD不能被其他疾病预测,只能预测ODD。CD仅由ODD预测。然而,ODD也直接预测未来的焦虑和抑郁,焦虑也预测未来的抑郁。对CD和抑郁症的失败模型的特定测试支持该模型。结论:ODD在年轻男性中作为一种关键的发育障碍出现,因为ODD对随后的行为和情感障碍都有显著影响。CD仅通过心理社会损害间接影响后期抑郁。焦虑先于抑郁,ADHD不能被其他疾病预测。
Background: This paper expands upon recent efforts to advance beyond the examination of concurrent comorbidity between affective and behavioral disorders by testing developmental sequences among disorders. Doing so allows for improved tests of theories, such as Capaldi and Patterson's failure model of Conduct Disorder (CD) and depression. Furthermore, Oppositional Defiant Disorder (ODD) is rarely considered distinctly from CD, minimizing the ability to identify distinct effects among behavioral disorders. Methods: This paper used data from the Developmental Trends Study, a clinic-referred cohort of 177 boys, along with their parents, who were assessed regularly using a structured clinical interview and a comprehensive set of other measures. Boys were recruited when they were between the ages of 7 and 12, and were reassessed annually until age 18. Predictive regression models tested the continuities among disorders, with depression, overanxious disorder, Attention Deficit Hyperactivity Disorder (ADHD), ODD and CD examined separately as outcomes. Results: Each disorder showed homotypic continuity, but a clear developmental sequence of heterotypic continuity also emerged. ADHD was predicted by no other disorders, and exclusively predicted ODD. CD was predicted only by ODD. However, ODD was also directly predictive of future anxiety and depression, and anxiety predicted future depression as well. A specific test of the failure model of CD and depression supported that model. Conclusion: ODD appears as a pivotal developmental disorder in young males, in that ODD is notably influential in both subsequent behavioral and affective disorders. CD influences later depression only indirectly, through psychosocial impairment. Anxiety precedes depression, and ADHD is not predicted by other disorders.