HIV decline associated with behavior change in Eastern Zimbabwe
HIV decline associated with behavior change in Eastern Zimbabwe
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DOI：
10.1126/science.1121054
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发表时间：
2006-02-03
期刊：
影响因子：
56.9
通讯作者：
Anderson, RM
中科院分区：
文献类型：
--
作者：
Gregson, S;Garnett, GP;Anderson, RM
在撒哈拉以南非洲国家中，艾滋病毒感染率下降的情况很少，只有乌干达有令人信服的证据表明艾滋病毒感染率下降是基于性行为的改变。我们报告了1998年至2003年津巴布韦东部地区艾滋病毒感染率的下降与四个不同社会经济阶层的性行为改变有关。艾滋病毒感染率在年轻人和受教育程度较高的人群中下降最快，在17至29岁的男性和15至24岁的女性中分别下降了23%和49%。有性经验的男性和女性报告说，随意性行为分别减少了49%和22%，而最近的队列报告说，延迟了首次性行为。艾滋病导致的选择性死亡率有助于艾滋病毒流行率的下降。
Few sub-Saharan African countries have witnessed declines in HIV prevalence, and only Uganda has compelling evidence for a decline founded on sexual behavior change. We report a decline in HIV prevalence in eastern Zimbabwe between 1998 and 2003 associated with sexual behavior change in four distinct socioeconomic strata. HIV prevalence fell most steeply at young ages-by 23 and 49%, respectively, among men aged 17 to 29 years and women aged 15 to 24 years-and in more educated groups. Sexually experienced men and women reported reductions in casual sex of 49 and 22%, respectively, whereas recent cohorts reported delayed sexual debut. Selective AIDS-induced mortality contributed to the decline in HIV prevalence.